D6750

Sodium deoxycholate

≥97% (titration)

• 동의어(들): 3α,12α-Dihydroxy-5β-cholanic acid sodium salt, 7-Deoxycholic acid sodium salt, Desoxycholic acid sodium salt
• 실험식(Hill 표기법): C₂₄H₃₉NaO₄
• CAS Number: 302-95-4
• Molecular Weight: 414.55
• Beilstein: 3581950
• EC Number: 206-132-7
• MDL number: MFCD00064139
• UNSPSC 코드: 12161900
• PubChem Substance ID: 24894044
• NACRES: NA.21

속성

• 설명: anionic
• Quality Level: 200
• 분석: ≥97% (titration)
• 형태: powder
• 분자량: micellar avg mol wt 1200-5000
• 응집 번호: 3-12
• CMC: 2-6 mM (20-25°C)
• solubility: water: 50 mg/mL, clear, colorless to light yellow
• HLB: 16
• 작용기: carboxylic acid
• 배송 상태: ambient
• 저장 온도: room temp
• SMILES string: [Na+].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC([O-])=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2
• InChI: 1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1
• InChI key: FHHPUSMSKHSNKW-SMOYURAASA-M

설명

일반 설명

Deoxycholic acid sodium salt, also known as Sodium Deoxycholate, is a highly versatile ionic detergent utilized for its exceptional ability to solubilize membrane-bound proteins and lyse cells. Its mechanism involves disrupting cell membranes and dissolving hydrophobic molecules, making it an invaluable reagent in scientific research applications. In protein research, it plays a pivotal role in solubilizing proteins, particularly those embedded in membranes, enabling their extraction, purification, and subsequent analysis.

Moreover, Sodium Deoxycholate extends its utility to nucleic acid extraction from cells and tissues. By lysing cells and disrupting cellular structures, it facilitates the release and purification of nucleic acids, proving valuable in cell biology and biochemical research. Beyond these applications, its effectiveness in cell lysis processes positions it as a valuable tool for breaking down cells and releasing their contents, finding applications in diverse biological studies, encompassing microscopy, cell biology, and biochemical research.

애플리케이션

Sodium deoxycholate has been used in the lysis buffer prepared for brown adipose tissue. It has been used in the decellularization of aortic valvular conduit.

생화학적/생리학적 작용

Solubilizes fats for absorption in the intestines.

특징 및 장점

Highly versatile surfactant for your cell biology and biochemical research

기타 정보

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안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves