M2772

Menthol

99%

• 동의어(들): 2-Isopropyl-5-methylcyclohexanol, Hexahydrothymol
• 실험식(Hill 표기법): C₁₀H₂₀O
• CAS Number: 89-78-1
• Molecular Weight: 156.27
• Beilstein: 3194263
• EC Number: 201-939-0
• MDL number: MFCD00001484
• UNSPSC 코드: 12352212
• PubChem Substance ID: 24896764
• NACRES: NA.25

속성

• vapor pressure: 0.8 mmHg ( 20 °C)
• Quality Level: 200
• 분석: 99%
• bp: 216 °C (lit.)
• mp: 34-36 °C (lit.)
• density: 0.89 g/mL at 25 °C (lit.)
• 응용 분야: metabolomics; vitamins, nutraceuticals, and natural products
• SMILES string: CC(C)C1CCC(C)CC1O
• InChI: 1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3
• InChI key: NOOLISFMXDJSKH-UHFFFAOYSA-N
• 유전자 정보: human ... TRPA1(8989) , TRPM8(79054)

설명

일반 설명

Menthol (C₁₀H₂₀O) is a terpenoid compound. It is extracted from the plants belonging to Mentha genus in the Lamiaceae family.

Menthol is a cyclic monoterpene alcohol, which is extracted from essential oils of Mentha canadensis and Mentha x piperita. It possesses antimicrobial, anticancer and anti-inflammatory properties. Menthol acts as a transient receptor potential cation channel (TRPM8) agonist. It also exhibits analgesic, antipruritic, anesthetic and cooling effects.

애플리케이션

Menthol has been used:

• to test its antifungal susceptibility
• to determine its efficacy as an anesthetic in fish
• to activate transient receptor potential cation channel (TRPM8)
• as an odorant for measuring sniffing dynamics

생화학적/생리학적 작용

Menthol exhibits antifungal action on the membrane permeability and the cell wall consistency, this might leads to cell death or inhibition of the C. albicans filamentation. Therefore, it can be used as a potential therapeutic agent for candidiasis. In addition to antifungal activity, menthol also exhibits anesthetic, antispasmodic, anti-ulcer and antiviral properties. It is considered as a safe compound for animal life. Therefore, Menthol is widely used in pharmaceuticals, cosmetics and food industries.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319
• 예방조치 성명서: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): 204.8 °F
• Flash Point (°C): 96 °C
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves