A8199

N-Acetyl-L-cysteine

≥99% (TLC), suitable for cell culture, BioXtra

• 동의어(들): LNAC, NAC
• Linear Formula: HSCH₂CH(NHCOCH₃)CO₂H
• CAS Number: 616-91-1
• Molecular Weight: 163.19
• Beilstein: 1724426
• EC Number: 210-498-3
• MDL number: MFCD00004880
• UNSPSC 코드: 12352209
• PubChem Substance ID: 24891213
• NACRES: NA.26

속성

• product name: N-Acetyl-L-cysteine, BioXtra, ≥99% (TLC)
• 제품 라인: BioXtra
• Quality Level: 300
• 분석: ≥99% (TLC)
• 형태: powder
• 기술: cell culture | mammalian: suitable
• 불순물: ≤0.002% Phosphorus (P); ≤0.1% Insoluble matter
• 무기 잔류물: ≤0.5%
• 색상: white to off-white
• mp: 106-108 °C (lit.)
• solubility: H₂O: 0.1 M at 20 °C, clear, colorless
• 양이온 미량물: Al: ≤0.0005%; Ca: ≤0.0005%; Cu: ≤0.0005%; Fe: ≤0.0005%; K: ≤0.005%; Mg: ≤0.0005%; NH₄⁺: ≤0.05%; Na: ≤0.1%; Pb: ≤0.001%; Zn: ≤0.0005%
• 응용 분야: cell analysis
• 저장 온도: 2-8°C
• SMILES string: CC(=O)N[C@@H](CS)C(O)=O
• InChI: 1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1
• InChI key: PWKSKIMOESPYIA-BYPYZUCNSA-N

설명

애플리케이션

N-Acetyl-L-cysteine has been used to study its protective effect against styrene-induced cochlear injuries in rats. It has also been used as a supplement in basal chemically-defined medium (BDM) for the culture of oligodendrocyte precursor cells.

생화학적/생리학적 작용

Antioxidant and mucolytic agent. Increases cellular pools of free radical scavengers. Reported to prevent apoptosis in neuronal cells but induce apoptosis in smooth muscle cells. Inhibits HIV replication. May serve as a substrate for microsomal glutathione transferase.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H319
• 예방조치 성명서: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)