모든 사진(2)

문서

37094

Rapamycin

Name: Rapamycin
Brand: SIAL

VETRANAL^®, analytical standard

동의어(들):

Sirolimus

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모든 사진(2)

About This Item

실험식(Hill 표기법):

C₅₁H₇₉NO₁₃

CAS Number:

53123-88-9

Molecular Weight:

914.17

MDL number:

MFCD00867594

UNSPSC 코드:

41116107

PubChem Substance ID:

329755624

NACRES:

NA.24

추천 제품

Slide 1 of 9

1 of 9

Sigma-Aldrich

553210

Rapamycin

Sigma-Aldrich

R0395

Rapamycin from Streptomyces hygroscopicus

Sigma-Aldrich

R8781

Rapamycin

Sigma-Aldrich

C0750

Caffeine

Sigma-Aldrich

553211

Rapamycin

Supelco

PHR1683

Celecoxib

Supelco

PHR1084

Metformin hydrochloride

Sigma-Aldrich

W222402

Caffeine

Sigma-Aldrich

C6628

Chloroquine diphosphate salt

Grade

analytical standard

Quality Level

100

제품 라인

VETRANAL^®

유통기한

limited shelf life, expiry date on the label

기술

HPLC: suitable
gas chromatography (GC): suitable

응용 분야

forensics and toxicology
pharmaceutical (small molecule)

형식

neat

저장 온도

−20°C

SMILES string

CO[C@@H]1C[C@@H](CC[C@H]1O)C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N4CCCC[C@H]4C(=O)O2)OC

InChI

1S/C51H79NO13/c1-30-16-12-11-13-17-31(2)42(61-8)28-38-21-19-36(7)51(60,65-38)48(57)49(58)52-23-15-14-18-39(52)50(59)64-43(33(4)26-37-20-22-40(53)44(27-37)62-9)29-41(54)32(3)25-35(6)46(56)47(63-10)45(55)34(5)24-30/h11-13,16-17,25,30,32-34,36-40,42-44,46-47,53,56,60H,14-15,18-24,26-29H2,1-10H3/b13-11+,16-12+,31-17+,35-25+/t30-,32-,33-,34-,36-,37+,38+,39+,40-,42+,43+,44-,46-,47+,51-/m1/s1

InChI key

QFJCIRLUMZQUOT-HPLJOQBZSA-N

유전자 정보

human ... FKBP1A(2280)

일반 설명

Rapamycin belongs to the macrolide class of antibiotics obtained from the bacterium Streptomyces hygroscopicus. It was first used as an anti-fungal agent but later also found use as an immunosuppressant and potential anti-cancer drug. It acts by preventing the activity of serine/threonine kinase and subsequently blocking the cytokine-driven T cell proliferation.

애플리케이션

The analytical standard can be used as follows:

Electrochemical determination of rapamycin using boron-doped diamond electrode and differential pulse voltammetry (DPV) in human urine, serum, and blood samples
Simultaneous determination of six immunosuppressants from whole blood samples by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) technique combined with modified QuEChERS method

기타 정보

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

법적 정보

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

픽토그램

GHS08

신호어

Warning

유해 및 위험 성명서

H351 - H361fd

예방조치 성명서

P201 - P202 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Carc. 2 - Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

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시험 성적서(COA)

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Sigma-Aldrich

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문서

Rapamycin