131164

Indigo carmine

certified by the Biological Stain Commission, Dye content 85 %

• 동의어(들): Acid Blue 74, Indigo-5,5′-disulfonic acid disodium salt, Indigocarmine
• 실험식(Hill 표기법): C₁₆H₈N₂Na₂O₈S₂
• CAS Number: 860-22-0
• Molecular Weight: 466.35
• 색상 지수 번호: 73015
• Beilstein: 4103904
• EC Number: 212-728-8
• MDL number: MFCD00005723
• UNSPSC 코드: 12171500
• PubChem Substance ID: 24847997
• NACRES: NA.47

속성

• Grade: certified by the Biological Stain Commission
• Quality Level: 200
• 분석: >85.0% (HPLC)
• 형태: solid
• 구성: Dye content, 85%
• 색상: dark blue to very dark blue
• pH: 3.87 (30 °C, 7.14 g/L)
• mp: ≥340 °C
• density: 0.71 g/cm³ at 29 °C
• λmax: 608 nm
• εmax: 20,000 at 250-256 nm in water at 0.01 g/L; 29500 at 284-290 nm in water at 0.01 g/L
• 응용 분야: diagnostic assay manufacturing; hematology; histology
• 저장 온도: room temp
• SMILES string: [Na+].[Na+].[O-]S(=O)(=O)c1ccc2NC(\C(=O)c2c1)=C3\Nc4ccc(cc4C3=O)S([O-])(=O)=O
• InChI: 1S/C16H10N2O8S2.2Na/c19-15-9-5-7(27(21,22)23)1-3-11(9)17-13(15)14-16(20)10-6-8(28(24,25)26)2-4-12(10)18-14;;/h1-6,17-18H,(H,21,22,23)(H,24,25,26);;/q;2*+1/p-2/b14-13+;;
• InChI key: KHLVKKOJDHCJMG-QDBORUFSSA-L

설명

애플리케이션

Indigo carmine has been used to investigate its effects on ozone production by neutrophils.

생화학적/생리학적 작용

Indigo Carmine (IC), commonly known as acid blue 74 or food blue 1 or FD and C blue 2 is a blue synthetic dye. It is used as a redox indicator in analytical chemistry and as a microscopic stain in biology. IC is also employed as a photometric detector. IC is a highly toxic indigoid dye and is associated with various health hazards such as irritation to the gastrointestinal tract leading to nausea, vomiting, and diarrhea and irritation in the respiratory tract leading to coughing and shortness of breath. IC exposure might also cause skin and eye irritations to humans. IC dye spray is used for the diagnosis of dysplasia in ulcerative colitis and is considered to be a simple, feasible, and safe method.

적합성

Used as a collagen stain and in procedures using red nuclear stains.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H317
• 예방조치 성명서: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Hazard Classifications: Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves