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Merck
모든 사진(2)

주요 문서

MCYTMAG-70K-PX32

Millipore

MILLIPLEX® Mouse Cytokine/Chemokine Magnetic Bead Panel - Premixed 32 Plex - Immunology Multiplex Assay

Simultaneously analyze multiple cytokine and chemokine biomarkers with Bead-Based Multiplex Assays using the Luminex technology, in mouse serum, plasma and cell culture samples.

동의어(들):

Luminex® Mouse cytokine immunoassay, Millipore Mouse cytokine immunoassay, Mouse cytokine Multiplex Assay

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About This Item

UNSPSC 코드:
12161503
eCl@ss:
32161000
NACRES:
NA.47

Quality Level

종 반응성

mouse

제조업체/상표

Milliplex®

assay range

accuracy: 85-107%
standard curve range: 3.2-10,000 pg/mL

기술

multiplexing: suitable

호환성

configured for Premixed

검출 방법

fluorometric (Luminex xMAP)

배송 상태

wet ice

일반 설명

The immune system is an organized complex network of biological structures and processes that protect against disease. For example, cytokine and chemokines mediate interactions between cells directly, regulating target immune cell responses. These responses result in inflammation where the immune system attempts to eradicate foreign antigens and begin the healing process. Consequently, the inflammatory process plays a key protective role in immunity. In addition, cytokine and chemokine research is essential in understanding the immune system and its multi-faceted response to most antigens, as well as disease states such as autoimmune disease, allergic reactions, sepsis, and cancer.

To identify specific cytokines involved in any inflammatory or immune response, it might be necessary to screen panels of cytokines, often requiring some level of automation and/or high throughput. Beads can make the process of automation and high throughput screening easier with features such as walk-away washing. Advantages even outside automation include:

More flexible plate and plate washer options
  • Improved performance with turbid serum/plasma samples
  • Assay results equivalent to non- beads
  • Automated washing avoids many problems associated with vacuum filtration washing


MILLIPLEX® Mouse Cytokine / Chemokine panel enables you to focus on the therapeutic potential of cytokines as well as the modulation of cytokine expression. Coupled with the Luminex® xMAP® platform in a bead format, you receive the advantage of ideal speed and sensitivity, allowing quantitative multiplex detection of dozens of analytes simultaneously, which can dramatically improve productivity.

Panel Type: Cytokines/Chemokines

특이성

Cross Reactivty
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.

애플리케이션

  • Analytes: Eotaxin/CCL11, G-CSF, GM-CSF, IFN-γ, IL-1α, IL-1β, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-9, IL-10, IL-12 (p40), IL-12 (p70), IL-13, IL-15, IL-17, IP-10, KC, LIF, LIX, MCP-1, M-CSF, MIG, MIP-1α, MIP-1β, MIP-2, RANTES, TNF-α, VEGF
  • Recommended Sample type: plasma, serum, or cell culture supernatant
  • Recommended Sample dilution: 1:2 diluted plasma or serum
  • Assay Run Time: Overnight or one day. For best results an overnight incubation is recommended.
  • Research Category: Inflammation & Immunology

포장

96 well plate
Premixed beads for your convenience.

저장 및 안정성

Recommended storage for kit components is 2 - 8°C.

기타 정보

Sensitivity: Refer to kit protocol for sensitivities for individual cytokines.

법적 정보

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

표적 기관

Respiratory Tract

Storage Class Code

10 - Combustible liquids


시험 성적서(COA)

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문서 라이브러리 방문

Alaa S Awad et al.
Kidney international, 88(4), 722-733 (2015-06-11)
Monocyte/macrophage recruitment correlates strongly with the progression of diabetic nephropathy. Tumor necrosis factor-α (TNF-α) is produced by monocytes/macrophages but the direct role of TNF-α and/or macrophage-derived TNF-α in the progression of diabetic nephropathy remains unclear. Here we tested whether inhibition
Erin S Calipari et al.
Nature communications, 9(1), 9-9 (2018-01-18)
Cocaine addiction is characterized by dysfunction in reward-related brain circuits, leading to maladaptive motivation to seek and take the drug. There are currently no clinically available pharmacotherapies to treat cocaine addiction. Through a broad screen of innate immune mediators, we
Takashi Hato et al.
The Journal of clinical investigation, 129(1), 296-309 (2018-12-07)
In response to viral pathogens, the host upregulates antiviral genes that suppress translation of viral mRNAs. However, induction of such antiviral responses may not be exclusive to viruses, as the pathways lie at the intersection of broad inflammatory networks that
Waleed Elsegeiny et al.
JCI insight, 3(12) (2018-06-22)
Despite the discovery of key pattern recognition receptors and CD4+ T cell subsets in laboratory mice, there is ongoing discussion of the value of murine models to reflect human disease. Pneumocystis is an AIDS-defining illness, in which risk of infection
Aswathy N Rai et al.
Scientific reports, 6, 26964-26964 (2016-06-02)
Streptococcus pneumoniae is the most common bacterial etiology of pneumococcal pneumonia in adults worldwide. Genomic plasticity, antibiotic resistance and extreme capsular antigenic variation complicates the design of effective therapeutic strategies. Polyamines are ubiquitous small cationic molecules necessary for full expression

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