MATFLAGELLIN

NEP Control Flagellin- PyroMAT^® System MAT

Non-endotoxin pyrogen control of flagellin for use in monocyte activation test

• 동의어(들): NEP, NEP Control
• UNSPSC 코드: 41116130
• eCl@ss: 32160606
• NACRES: NA.24

속성

• 분석: ≥95% (SDS-PAGE)
• Quality Level: 400
• 사용: sufficient for 10 tests
• 특징: Non-endotoxin pyrogen control of flagellin for use in monocyte activation test
• 제조업체/상표: PyroMAT^®
• 응용 분야: pharmaceutical; pyrogen testing
• 호환성: configured for PyroDetect System; configured for PyroMAT^® System
• 배송 상태: cooler
• 저장 온도: −20°C
• 적합성: pyrogenic bacteria

설명

일반 설명

The PyroMAT^® System uses cryopreserved Mono-Mac-6 (MM6) human monocytic cells as a source of monocytes. The response to a full range of pyrogens, including endotoxins and non-endotoxin pyrogens (NEPs)is determined by the measurement of interleukin-6 (IL-6) produced by the Mono-Mac-6 cells using ELISA.
NEP control flagellin is a preparation of flagellin from Salmonella typhimurium and supplied in a lyophilized form. Flagellin is a non-endotoxin pyrogen (NEP) that activates the TLR5 receptor of monocytes and can be used as a positive control with the PyroMAT^® System (Monocyte Activation Test for pyrogen detection).

특이성

TLR-5 agonist

애플리케이션

NEP control of flagellin can be used as a positive control with the PyroMAT^® System. It is to be used for Product Specific Validation (PSV) and routine testing to show that the system can detect non-endotoxin pyrogen contaminants in pharmaceutical products.

특징 및 장점

Endotoxin-free product at concentration of use in MAT Purity: ≥ 95% (SDS-PAGE)

저장 및 안정성

Store unopened vials at -20°C
Do not use unopened vials after expiration date
Store resuspended aliquots at -20°C
Shelf life of aliquots can be found on the technical datasheet

법적 정보

PYROMAT is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable