MABT39

Anti-Laminin alpha 5 Antibody, clone 4B12

clone 4B12, from mouse

• 동의어(들): laminin, alpha 5, Laminin-15 subunit alpha, laminin alpha-5 chain, Laminin-11 subunit alpha, laminin subunit alpha-5, Laminin-10 subunit alpha, Laminin α5, Lamininα5, Laminin-α5
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 항체 형태: purified antibody
• 항체 생산 유형: primary antibodies
• 클론: 4B12, monoclonal
• 종 반응성: human
• 기술: immunohistochemistry: suitable
• 동형: IgG1λ
• NCBI 수납 번호: NP_005551
• UniProt 수납 번호: O15230
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... LAMA5(3911)

설명

일반 설명

Laminin alpha 5 (α5) is a member of the laminin family of extracellular matrix glycoproteins. Laminin’s are important in cell migration, differentiation and in tumor cell incursion. Research shows that laminin alpha 5 may be an early marker of sexual differentiation. In rat, the laminin alpha 5 chain seems to halt expression in the basement membrane of Sertoli cells when secretion of AMH begins but expression increases two weeks after birth when AMH secretion stops. Laminin alpha 5 shows up early during lung development in mice. It has also been linked to inflammatory cell chemotaxis and metalloproteinase activity and may play a role in creating and sustaining mucosal patterns of the mouse small intestine.

면역원

Laminin purified from human placenta

애플리케이션

Immunohistochemistry Analysis: A 1:100 dilution from a representative lot detected Laminin alpha 5 in human blood vessels and metastatic colorectal adenocarcinoma tissues.

Research Category
Cell Structure

Research Sub Category
ECM Proteins

This Anti-Laminin alpha 5 Antibody, clone 4B12 is validated for use in IH for the detection of Laminin alpha 5.

품질

Evaluated by Immunohistochemistry in human precancerous colorectal lesion tissue.

Immunohistochemistry Analysis: A 1:100 dilution of this antibody detected Laminin alpha 5 in human precancerous colorectal lesion tissue.

표적 설명

400 kDa calculated

물리적 형태

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG1λ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

분석 메모

Control
Human precancerous colorectal lesion tissue

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable