MABC662

Anti-RIPK2 Antibody, clone 1H10.1

clone 1H10.1, from mouse

• 동의어(들): Receptor-interacting serine/threonine-protein kinase 2, CARD-containing interleukin-1 beta-converting enzyme-associated kinase, CARD-containing IL-1 beta ICE-kinase, RIP-like-interacting CLARP kinase, Receptor-interacting protein 2, RIP-2, Tyrosine-prote
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 1H10.1, monoclonal
• 종 반응성: human
• 기술: immunohistochemistry: suitable; western blot: suitable
• 동형: IgMκ
• NCBI 수납 번호: NP_003812
• UniProt 수납 번호: O43353
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... RIPK2(8767)

설명

일반 설명

Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1; EC 2.7.10.2; UniProt O43353; also known as Receptor-interacting protein 2, CARD-carrying kinase, CARD-containing IL-1 beta ICE-kinase, CARD-containing interleukin-1 beta-converting enzyme-associated kinase, Growth-inhibiting gene 30, Receptor-interacting protein-like interacting caspase-like apoptosis regulatory protein kinase, RIP-2, RIP-like interacting CLARP kinase, Tyrosine-protein kinase RIPK2) is encoded by the RIPK2 (also known as CARD3, CARDIAK, CCK, GIG30, RICK, RIP2) gene (Gene ID 8767) in human. RIPK2 is a dual-specificity kinase that exhibits both serine/threonine as well as tyrosine kinase activities. RIPK2 participates in transducing cellular inflammatory response by propagating signaling downstream of the intracellular peptidoglycan sensors NOD1 and NOD2.

특이성

Expected to react with both isoforms.

면역원

GST-tagged recombinant protein corresponding to human RIPK2.

애플리케이션

Anti-RIPK2 Antibody, clone 1H10.1 is an antibody against RIPK2 for use in Western Blotting and Immunohistochemistry.

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected RIPK2 in human prostate and human placenta tissue.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

품질

Evaluated by Western Blotting in human placenta tissue lysate.

Western Blotting Analysis: A 1:500 dilution of this antibody detected RIPK2 in 10 µg of human placenta tissue lysate.

표적 설명

~60 kDa observed

물리적 형태

Format: Purified

Purified mouse monoclonal IgMκ antibody in PBS with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

기타 정보

Concentration: Please refer to lot specific datasheet.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable