HSCRMAG-32K

MILLIPLEX^® Human Soluble Cytokine Receptor Panel- Immunology Multiplex Assay

Simultaneously analyze multiple cytokine and chemokine biomarkers with Bead-Based Multiplex Assays using the Luminex technology, in human serum, plasma and cell culture samples.

• 동의어(들): Human Cytokine Receptor Multiplex Kit, Luminex^® Human Cytokine Receptor Immunoassay, Millipore Cytokine Receptor Panel
• UNSPSC 코드: 12161503
• eCl@ss: 32161000
• NACRES: NA.84

속성

• Quality Level: 200
• 종 반응성: human
• 제조업체/상표: Milliplex^®
• assay range: accuracy: 91-104%; sensitivity: 4-208 pg/mL; (Overnight Incubation minDC); standard curve range: 12.2-50,000 pg/mL; (sIL-4R, sIL-6R, sRAGE, sTNFRI, sTNFRII); standard curve range: 122.1-500,000 pg/mL; (sEGFR, sIL-1RII, sVEGF-R1, sVEGF-R2, sVEGF-R3); standard curve range: 24.4-100,000 pg/mL; (sCD30, sgp130, sIL-1RI, sIL-2Rα); inter-assay cv: <15%; intra-assay cv: <10%
• 기술: multiplexing: suitable
• 검출 방법: fluorometric (Luminex xMAP)
• 배송 상태: wet ice

설명

일반 설명

Cytokine receptors constitute an integral part of cytokine biology. Like cytokines, cytokine receptors are involved in normal physiological and pathological processes of almost all disease states. Soluble cytokine receptors naturally arise from genes encoding membrane- bound receptors or are direct derivatives of the receptors themselves. The discovery that soluble cytokine receptors are involved in regulating excessive inflammatory responses and modulating immune events has stimulated significant research interest in their potential role as immunotherapeutic agents. Many of these soluble cytokine receptors can inhibit the binding and biological activity of their cytokine ligands, making them very specific cytokine antagonists.

MILLIPLEX^® Human Soluble Cytokine Receptor Panel is to be used for the simultaneous quantification of 14 soluble cytokine receptors in human serum, plasma and cell / tissue culture supernatant samples. This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.

The Luminex^® xMAP^® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Cytokines/Chemokines

애플리케이션

• Analytes: sCD30, sEGFR, sGP130, sIL-1RI, sIL-1RII, sIL-2Rα, sIL-4R, sIL-6R, sRAGE, sTNFRI, sTNFRII, sVEGFR1, sVEGFR2, sVEGFR3
• Recommended Sample type: Serum, plasma or tissue/cell lysate and culture supernatant
• Recommended Sample dilution: 1:5 dilution for plasma or serum or neat cell culture supernatant
• Assay Run Time: Overnight
• Research Category: Inflammation & Immunology

특징 및 장점

Design your multiplex kit by choosing available analytes within this panel.

기타 정보

Please contact Technical Service for linearity of dilution.

Sensitivity: Please see kit protocol for individual assay sensitivities.

법적 정보

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

안전성 정보

• 픽토그램: GHS08,GHS05,GHS07,GHS09
• 신호어: Danger
• 유해 및 위험 성명서: H302 + H312 + H332,H317,H318,H373,H411
• 예방조치 성명서: P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P314
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
• 표적 기관: Respiratory Tract
• Storage Class Code: 10 - Combustible liquids