FCMAB203P

Milli-Mark^® Anti-CD64-PE Antibody, clone 10.1

clone 10.1, Milli-Mark^®, from mouse

• 동의어(들): High affinity immunoglobulin gamma Fc receptor I, IgG Fc receptor I, Fc-gamma RIA, FcgammaRIa, Fc-gamma RI, FcRI
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.44

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 결합: PE
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 10.1, monoclonal
• 종 반응성: human
• 제조업체/상표: Milli-Mark^®
• 기술: flow cytometry: suitable
• 동형: IgG1κ
• NCBI 수납 번호: NP_000034.1
• UniProt 수납 번호: P12314
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... FCGR1A(2209)

설명

일반 설명

CD64 is the high-affinity IgG Fc receptor belonging to the immunoglobulin supergene family (Guyre, 2002). CD64 is a 72 kDa glycoprotein which binds monomeric IgG (human IgG>>IgG>>>IgG4>>>IgG2 and mouse IgG3>IgG2a>>>IgG1, IgG2b). Three genes: FcγR1A, FcγR1B and FcγR1C, which have >98 percent identity at the nucleotide level, have been identified and mapped to chromosome 1, band q21.1 (Sun,1997)). The FcγR1A gene, which specified the high-affinity IgG receptor, encodes three C2-type Ig-like extracellular domains, a 21 amino acid transmembrane region, and a charge cytoplasmic tail of 61 amino acids (Sun, 1997)(van de Winkel,1993).

특이성

Antibody recognizes Human CD64 antigen.

면역원

Human rheumatoid synovial fluid cells and monocytes.

애플리케이션

Milli-Mark Anti-CD64-PE Antibody, clone 10.1 detects level of CD64 & has been published & validated for use in FC.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

품질

Evaluated by flow cytometry using human PBMCs

표적 설명

72 kDa (Sun W, 1997)

물리적 형태

Protein A purified

Purified Mouse monoclonal IgG1 conjugated to PE in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

저장 및 안정성

Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.

분석 메모

Control
PBMC′s

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

법적 정보

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable