추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
fractionated antiserum
항체 생산 유형
primary antibodies
클론
polyclonal
형태
lyophilized powder
종 반응성
human, bovine, rat
기술
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
indirect ELISA: suitable
western blot: 1:1,000
불순물
endotoxin, tested
UniProt 수납 번호
응용 분야
research pathology
저장 온도
2-8°C
타겟 번역 후 변형
unmodified
유전자 정보
bovine ... FGF2(281161)
human ... FGF2(2247)
rat ... Fgf2(54250)
일반 설명
Fibroblast growth factor-basic (FGFb), also known as NUDT6 (nudix (nucleoside diphosphate linked moiety X)-type motif 6) is encoded by the gene mapped to human chromosome 4q28.1. The FGFb gene spanning 34271 bp on genomic DNA contains 16 exons and six introns. FGFb RNA transcripts are expressed in various human tissues including liver, thymus, spleen, peripheral blood leukocytes, heart skeletal muscle, testis, colon and kidney.
면역원
synthetic peptide sequence corresponding to bovine FGF2 (1-24).
애플리케이션
Anti-Fibroblast Growth Factor-Basic (1-24) antibody produced in rabbit has been used in:
- immunohistochemistry
- immunostaining
- immunoblotting
생화학적/생리학적 작용
Fibroblast Growth Factor Basic (also known as bFGF) is a pleotropic cytokine that that is a potent mitogenic factor. On binding to its cognate receptor tyrosine kinase, FGFR, bFGF is capable of activation of pathways such as MAPK and PI3K and produce cellular effects in varied cell types. Fibroblast Growth Factor-basic is reported to induce proliferation of fibroblasts, differentiation, wound healing and regeneration, limb formation, tissue remodeling and angiogenesis.
물리적 형태
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.
분석 메모
Bioactivity: Anti-Fibroblast Growth Factor-Basic (1-24) caused a dose-dependent decrease in the mitogenic activity of FGF-Basic such that a final dilution of 1:50 neutralized the bioactivity of 1 unit of FGF Basic.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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관련 제품
제품 번호
설명
가격
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
B G Condron
Neuron, 24(3), 531-540 (1999-12-14)
In the grasshopper CNS, serotonergic growth cones cross the midline early in development and initiate expression of serotonin uptake activity, or SERT. To test if the midline contains an activity that induces SERT, cuts were made that separated serotonergic cell
Effect of human umbilical cord blood mesenchymal stem cells administered by intravenous or intravitreal routes on cryo-induced retinal injury
Mohamed EM, et al.
IUBMB Life, 69(3), 188-201 (2017)
Correlation of astrocyte elevated gene-1, basic-fibroblast growth factor, beta-catenin, Ki-67, tumor necrosis factor-alfa with prognostic parameters in ductal carcinomas and ductal intraepithelial neoplasms
Erdem H, et al.
Nigerian Journal of Clinical Practice, 18(5), 638-643 (2015)
Natale Belluardo et al.
Brain research, 1193, 12-24 (2008-01-15)
Precursor cell proliferation is present in the subventricular zone (SVZ) of the lateral ventricles and the subgranular zone (SGZ) of the dentate gyrus of the hippocampus of adult rat and persists during aging although at reduced levels. Previous studies have
Joost F M Lensen et al.
Journal of the American Society of Nephrology : JASN, 16(5), 1279-1288 (2005-03-25)
Glycosaminoglycans (GAG) play an important role in renal homeostasis. They are strongly negatively charged polysaccharides that bind and modulate a myriad of proteins, including growth factors, cytokines, and enzymes. With the aid of specific phage display-derived antibodies, the distribution of
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