ABN445

Anti-ARL13B Antibody

from rabbit, purified by affinity chromatography

• 동의어(들): ARL13B, ARL2-like protein 1, ADP-ribosylation factor-like protein 13B, ADP-ribosylation factor-like protein 2-like 1
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 정제법: affinity chromatography
• 종 반응성: human, mouse
• 기술: immunohistochemistry: suitable; western blot: suitable
• NCBI 수납 번호: NP_878899
• UniProt 수납 번호: Q3SXY8
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... ARL13B(200894)

설명

일반 설명

ARL13B/ARL2L1 is an important neuronal developmental protein, as well as, a cilium-specific protein required for the control of the microtubule-based ciliary axoneme structure. ARL13B/ARL2L1 is required for proper patterning in neural development during neural tube formation, and ARL13B/ARL2L1 is critical for cerebral cortex development and the initial polarization of radial glia scaffold, the first step in cortex development. ARL13B/ARL2L1 also controls the migration and placement of post mitotic interneurons. ARL13B/ARL2L1 is found in cellular projections and cilium and is widely expressed in the developing system as well in the gut. ARL13B/ARL2L1 also is a member of the small GTPase superfamily as it binds GTP but does not cleave it.

면역원

KLH-conjugated linear peptide corresponding to human ARL13B.

애플리케이션

Anti-ARL13B Antibody is an antibody against ARL13B for use in Immunohistochemistry and Immunocytochemistry.

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected ARL13B in human cerebellum, embryonic mouse liver, and human cerebral cortex tissue.

Research Category
Neuroscience

Research Sub Category
Developmental Signaling

품질

Evaluated by Western Blotting in mouse E13-14 brain tissue lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected ARL13B in 10 µg of mouse E13-14 brain tissue lysate.

표적 설명

~60 kDa observed. Western blot shows the absence of a 60 kDa Arl13b band in Arl13bE9.5 (Humbert, M.C., et al. (2012). PNAS. 109(48):19691-19696).

물리적 형태

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

기타 정보

Concentration: Please refer to lot specific datasheet.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable