8.52111

Fmoc-Lys(Me)₂-OH HCl

≥95.0% (HPLC), for peptide synthesis, Novabiochem^®

• 동의어(들): Fmoc-Lys(Me)₂-OH HCl, N-α-Fmoc-N-ε-dimethyl-N-L-lysine · hydrochloride
• 실험식(Hill 표기법): C₂₃H₂₈N₂O₄ · xHCl
• CAS Number: 252049-10-8
• Molecular Weight: 396.48 (free base basis)
• MDL number: MFCD05662353
• UNSPSC 코드: 12352209
• NACRES: NA.22

속성

• 제품명: Fmoc-Lys(Me)₂-OH HCl, Novabiochem^®
• Quality Level: 200
• 제품 라인: Novabiochem^®
• 분석: ≥95% (TLC); ≥95.0% (HPLC)
• 양식: powder
• 반응 적합성: reaction type: Fmoc solid-phase peptide synthesis
• 제조업체/상표: Novabiochem^®
• 응용 분야: peptide synthesis
• 작용기: amine
• 저장 온도: -10 to -25°C
• SMILES string: Cl.N([C@@H](CCCCN(C)C)C(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3
• InChI: 1S/C23H28N2O4.ClH/c1-25(2)14-8-7-13-21(22(26)27)24-23(28)29-15-20-18-11-5-3-9-16(18)17-10-4-6-12-19(17)20;/h3-6,9-12,20-21H,7-8,13-15H2,1-2H3,(H,24,28)(H,26,27);1H/t21-;/m0./s1
• InChI key: SJFAFKDBWNFBCC-BOXHHOBZSA-N

설명

일반 설명

A novel derivative for the introduction of dimethyl-lysine during Fmoc SPPS. Ref ^[1] contains methods and protocols for the synthesis of arrays of histone-related peptides containing methylated arginine and lysine-residues.


Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Overcoming Aggregation in Fmoc SPPS

Literature references

^[1] S. Rothbart, et al. (2012) Methods Enzymol., 512, 107.

결합

Replaces: 04-12-1269

분석 메모

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(CMA1)): ≥ 95 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Acetate (IC): ≤ 1.0 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

법적 정보

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable