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Merck
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Key Documents

662047

Sigma-Aldrich

Anti-Uncoupling Protein-2 (UCP-2) (144-157) Rabbit pAb

liquid, Calbiochem®

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

항체 형태

purified antibody

항체 생산 유형

primary antibodies

클론

polyclonal

형태

liquid

포함

0.1% sodium azide as preservative

종 반응성

human, mouse, rat

제조업체/상표

Calbiochem®

저장 조건

OK to freeze
avoid repeated freeze/thaw cycles

동형

IgG

배송 상태

wet ice

저장 온도

−70°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... UCP2(7351)

일반 설명

Protein A purified rabbit polyclonal antibody. Recognizes the UCP-2 protein.
Recognizes the UCP-2 protein.

면역원

a synthetic peptide [(C)QARAGGGRRYQSTV] corresponding to amino acids 144-157 of human and mouse UCP-2

애플리케이션

ELISA (1:100,000)

Immunoblotting (1:1000)

Immunocytochemistry (1:500)

포장

Please refer to vial label for lot-specific concentration.

경고

Toxicity: Standard Handling (A)

기타 정보

Does not react with UCP-1 or UCP-3. Since this antigen sequence is highly conserved, cross-reactivity across a broad range of species is expected. Variables associated with assay conditions will dictate the proper working dilution.
Stuart, J.A., et al. 2001. J. Biol. Chem.276, 18633.
Gimeno, R.E., et al. 1997. Diabetes46, 900.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Jay D Turner et al.
Circulation research, 106(4), 730-738 (2010-01-09)
Uncoupling protein (UCP)2 is a mitochondrial inner membrane protein that is expressed in mammalian myocardium under normal conditions and upregulated in pathological states such as heart failure. UCP2 is thought to protect cardiomyocytes against oxidative stress by dissipating the mitochondrial
P Brauner et al.
Pediatric research, 49(3), 440-447 (2001-03-03)
Hepatic hematopoiesis is prominent during fetal life and ceases around birth. In rodent liver, the decline of the hepatic hematopoiesis starts abruptly at birth being accompanied by a decrease of mitochondrial uncoupling protein 2 (UCP2) expression in monocytes/macrophages, whereas hepatocytes
Anjum Dihingia et al.
Scientific reports, 8(1), 10021-10021 (2018-07-04)
This study for the first time examined the prophylactic role of Tungrymbai, a well-known fermented soybean food of North-East India, against hepatic steatosis. Treatment with hexane-isopropanolic (2:1, HIET) but not hydro-alcoholic (70% ethanol, HAET) extract dose-dependently (0.1, 0.2, or 0.3 µg/mL)
Jong-Seok Moon et al.
The Journal of clinical investigation, 125(2), 665-680 (2015-01-13)
Cellular lipid metabolism has been linked to immune responses; however, the precise mechanisms by which de novo fatty acid synthesis can regulate inflammatory responses remain unclear. The NLRP3 inflammasome serves as a platform for caspase-1-dependent maturation and secretion of proinflammatory

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