581500

TEMPOL

≥95% (HPLC), crystals,powder, free radical scavenger and nitric oxide spin trap, Calbiochem^®

• 동의어(들): TEMPOL, 4-Hydroxy-TEMPO, 4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl
• 실험식(Hill 표기법): C₉H₁₈NO₂
• CAS Number: 2226-96-2
• Molecular Weight: 172.24
• MDL number: MFCD00006478
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• 제품명: TEMPOL, A stable, cell-permeable nitroxide that acts as a free radical scavenger and nitric oxide spin trap.
• Quality Level: 100
• 분석: ≥95% (HPLC)
• 양식: crystals; powder
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; protect from light
• 색상: orange
• solubility: DMSO: 5 mg/mL; ethanol: soluble; water: soluble
• 배송 상태: ambient
• 저장 온도: −20°C
• InChI: 1S/C9H18NO2/c1-8(2)5-7(11)6-9(3,4)10(8)12/h7,11H,5-6H2,1-4H3
• InChI key: UZFMOKQJFYMBGY-UHFFFAOYSA-N

설명

일반 설명

A stable, cell-permeable nitroxide free radical that acts as a radical scavenger and nitric oxide spin trap. Induces oxidative stress and enhances the levels of p21^WAF1 in HL-60 cells in a dose-dependent manner. Reported to reduce organ injury following hemorrhagic shock. Exhibits radio-protective and anti-proliferative properties.

A stable, cell-permeable nitroxide that acts as a free radical scavenger and nitric oxide spin trap. Induces oxidative stress and enhances the levels of p21^WAF1 in HL-60 cells in a dose-dependent manner. Reported to reduce organ injury following hemorrhagic shock. Exhibits radio-protective and anti-proliferative properties.

생화학적/생리학적 작용

Cell permeable: yes

Primary Target
Free radical scavenger and nitric oxide spin trap

Product does not compete with ATP.

Reversible: no

포장

Packaged under inert gas

경고

Toxicity: Harmful (C)

재구성

Prepare fresh solutions. Following reconstitution, aliquot and freeze (-20°C).

기타 정보

Gariboldi, M.B., et al. 2000. Free Radic. Biol. Med.29, 633.
Miura, Y., et al. 2000. J. Radiat. Res. (Tokyo)41, 103.
Mota-Filipe, H., et al. 1999. Shock 12, 255.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS08,GHS05,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H302,H318,H373
• 예방조치 성명서: P260 - P264 - P280 - P301 + P312 - P305 + P351 + P338 - P314
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - STOT RE 2 Oral
• 표적 기관: Liver,spleen
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): 294.8 °F - DIN 51758
• Flash Point (°C): 146 °C - DIN 51758