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Merck
모든 사진(1)

주요 문서

모든 문서 보기

567540

Sigma-Aldrich

Sodium Orthovanadate

A broad spectrum potent inhibitor of protein tyrosine phosphatases.

동의어(들):

Sodium Orthovanadate, PTP Inhibitor X

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모든 사진(1)

About This Item

실험식(Hill 표기법):
Na3O4V
CAS Number:
13721-39-6
Molecular Weight:
183.91
MDL number:
MFCD00003511
UNSPSC 코드:
12352202
NACRES:
NA.77

Quality Level

100

설명

RTECS - YW1120000

양식

solid

제조업체/상표

Calbiochem®

저장 조건

OK to freeze

색상

white to off-white

solubility

water: 10 mg/mL

배송 상태

ambient

저장 온도

10-30°C

SMILES string

[V](=O)([O-])([O-])[O-].[Na+].[Na+].[Na+]

InChI

1S/3Na.4O.V/q3*+1;;3*-1;

InChI key

IHIXIJGXTJIKRB-UHFFFAOYSA-N

일반 설명

A broad spectrum potent inhibitor of protein tyrosine phosphatases. Also known to inhibit Na+/K+ ATPase, acid and alkaline phosphatases, phosphofructokinase, and adenylate kinase. Most recently shown to inhibit ATPase activity of the reconstituted binding protein-dependent ATP-Binding Cassette (ABC) transporter for maltose (MalFGK2) of Salmonella typhimurium in the micromolar range. Can be converted to pervanadate by hydrogen peroxide.

생화학적/생리학적 작용

Cell permeable: no
Primary Target
Na+,K+-ATPase, acid , alkaline phosphatases, phosphofructokinase, and adenylate kinase
Product does not compete with ATP.
Reversible: no

경고

Toxicity: Harmful (C)

재구성

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

기타 정보

Huyer, G., et al. 1997. J. Biol. Chem. 272, 843.
Hunke, S., et al. 1995. Biochem. Biophys. Res. Commun.216, 589.
Levchuck, S.G., et al. 1994. Pediatric Res.37, 382A.
Fohr, K.J., et al. 1989. Biochem. J.262, 83.
Swarup, G., et al. 1982. Biochem. Biophys. Res. Commun.107, 1104.
Seargeant, L.E. and Stinson, R.A. 1979. Biochem. J.181, 247.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

픽토그램

Exclamation mark
GHS07

신호어

Warning

유해 및 위험 성명서

H302 + H312 + H332,H315,H319

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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