5.04841

5,7-Dichlorokynurenic Acid, Sodium Salt

• 동의어(들): 5,7-Dichlorokynurenic Acid, Sodium Salt, 5,7-Dichloro-4-hydroxyquinoline-2-c-arboxylic acid sodium salt, DCKA
• 실험식(Hill 표기법): C₁₀H₄Cl₂NNaO₃
• CAS Number: 1184986-70-6
• Molecular Weight: 280.04
• UNSPSC 코드: 12352106
• NACRES: NA.77

속성

• 분석: ≥99% (HPLC)
• Quality Level: 100
• 형태: solid
• 효능: 79 nM K_i
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; protect from light
• 색상: white
• solubility: water: 10 mM; 1 M NaOH: 100 mM
• 저장 온도: 2-8°C
• InChI: 1S/C10H5Cl2NO3.Na/c11-4-1-5(12)9-6(2-4)13-7(10(15)16)3-8(9)14;/h1-3H,(H,13,14)(H,15,16);/q;+1/p-1
• InChI key: VPRPMJHKWHCUFW-UHFFFAOYSA-M

설명

일반 설명

A very potent, water-soluble antagonist of the NMDA receptors complex acting at the strychnine-insensitive glycine binding site (K_i = 79 nM vs. [3H]-glycine).

생화학적/생리학적 작용

Primary Target
NMDA receptors

경고

Toxicity: Standard Handling (A)

재구성

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

기타 정보

Baron, B., et al. 1991. Eur. J. Pharmacol.206, 149.
Baron, B., et al. 1990. Mol. Pharmacol.38, 554.
Mugnaini, M., et al. 1998. J. Recept. Signal Transduct. Res.18, 91.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable