444241

MMP-2/MMP-9 Inhibitor I

The MMP-2/MMP-9 Inhibitor I, also referenced under CAS 193807-58-8, controls the biological activity of MMP-2/MMP-9. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

• 동의어(들): MMP-2/MMP-9 Inhibitor I, (2R)-2-[(4-Biphenylylsulfonyl)amino]-3-phenylpropionic Acid
• 실험식(Hill 표기법): C₂₁H₁₉NO₄S
• CAS Number: 193807-58-8
• Molecular Weight: 381.44
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥95% (HPLC)
• 양식: solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze
• 색상: white
• solubility: DMSO: 200 mg/mL
• 배송 상태: ambient
• 저장 온도: −20°C

설명

일반 설명

A potent inhibitor of MMP-2 (IC₅₀ = 310 nM) and MMP-9 (IC₅₀ = 240 nM). Orally active in animal models of tumor growth and metastasis.

A potent inhibitor of MMP-2 (gelatinase A; IC₅₀ = 310 nM) and MMP-9 (gelatinase B; IC₅₀ = 240 nM).

생화학적/생리학적 작용

Cell permeable: no

Primary Target
MMP-2, MMP-9

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 310 nM and 240 nM against MMP-2 and MMP-9

포장

Packaged under inert gas

경고

Toxicity: Standard Handling (A)

재구성

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

기타 정보

Tamura, Y., et al. 1998. J. Med. Chem.41, 640.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable