437694

DL-α-Lipoic Acid, Dihydro-

An effective antioxidant.

• 동의어(들): DL-α-Lipoic Acid, Dihydro-, DHLA, Dihydrolipoic Acid, Thiocytic Acid, Dihydro-
• 실험식(Hill 표기법): C₈H₁₆O₂S₂
• CAS Number: 462-20-4
• Molecular Weight: 208.34
• MDL number: MFCD00166974
• UNSPSC 코드: 12352106
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥95% (TLC)
• 형태: liquid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; protect from light
• 색상: light yellow
• solubility: ethanol: 50 mg/mL
• 배송 상태: ambient
• 저장 온도: 2-8°C
• InChI: 1S/C8H16O2S2/c9-8(10)4-2-1-3-7(12)5-6-11/h7,11-12H,1-6H2,(H,9,10)
• InChI key: IZFHEQBZOYJLPK-UHFFFAOYSA-N

설명

일반 설명

An effective antioxidant. Scavenges hypochlorous acid, peroxyl, superoxide, hydroxyl and nitric oxide radicals. Also exhibits prooxidant properties, as demonstrated by its ability to reduce iron ions and to generate reactive sulfur-containing radicals that can damage certain proteins, such as α₁-antiproteinase and creatine kinase. DHLA has recently been shown to inhibit apoptosis in rat thymocytes induced by methylprednisolone and etoposide.

An effective antioxidant. Scavenges hypochlorous acid, peroxyl, superoxide, hydroxyl, and nitric oxide radicals. Also exhibits prooxidant properties, as demonstrated by its ability to reduce iron ions and to generate reactive sulfur-containing radicals that can damage certain proteins, such as α₁-antiproteinase and creatine kinase. DHLA has recently been shown to inhibit apoptosis in rat thymocytes induced by methylprednisolone and etoposide.

생화학적/생리학적 작용

Cell permeable: no

Primary Target
Scavenges hypochlorous acid, peroxyl, superoxide, hydroxyl, and nitric oxide radicals

Product does not compete with ATP.

Reversible: no

포장

Packaged under inert gas

경고

Toxicity: Irritant (B)

기타 정보

Packer, L., et al. 1997. Adv. Pharmacol. 38, 79.
Bustamante, J., et al. 1995. Free Radic. Biol. Med. 19, 339.
Scott, B.C., et al. 1994. Free Radic. Res. 20, 119.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS05,GHS07,GHS09
• 신호어: Danger
• 유해 및 위험 성명서: H302,H315,H317,H318,H411
• 예방조치 성명서: P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): 348.1 °F - Cleveland open cup
• Flash Point (°C): 175.6 °C - Cleveland open cup