345752

Ganglioside GD₃, Disialo, Diammonium Salt, Bovine Buttermilk

Has been characterized as one of the most important tumor-specific antigens in individuals with malignant melanoma.

• 동의어(들): Ganglioside GD₃, Disialo, Diammonium Salt, Bovine Buttermilk, Neu5Acα2,8Neu5Acα2,3Galβ1,4Glcβ1,1 Ceramide, 2NH₄
• 실험식(Hill 표기법): C₇₀H₁₂₃N₃O₃₀ · 2NH₄
• Molecular Weight: 1522.80
• UNSPSC 코드: 12352211
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (TLC)
• 양식: solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze
• 색상: white
• solubility: water: 1 mg/mL; chloroform/methanol (2:1): soluble
• 배송 상태: ambient
• 저장 온도: −20°C

설명

일반 설명

Has been characterized as one of the most important tumor-specific antigens in individuals with malignant melanoma. Reported to disrupt mitochondrial transmembrane potential and induce apoptosis in tumor cells by a caspase-independent mechanism. Antibodies to GD₃ can induce partial remission of tumor growth in animals and in humans via enhancement of cytotoxic and proliferative responses of lymphocytes. M.W. 1577.0 (based on tricosanoyl - 23:0).

경고

Toxicity: Irritant (B)

기타 정보

DeMaria, R., et al. 1997. Science 277, 1652.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable