234567M

Concanavalin A, Canavalia ensiformis

Concanavalin A, Canavalia ensiformis, CAS 11028-71-0, is a carbohydrate-binding protein that agglutinates various animal cells. Restores the growth pattern of tumor cells to that of normal cells.

• 동의어(들): Concanavalin A, Canavalia ensiformis, Con A, Jack Bean Hemagglutinin
• CAS Number: 11028-71-0
• MDL number: MFCD00071069
• UNSPSC 코드: 12352202
• NACRES: NA.42

속성

• Quality Level: 100
• 설명: Merck USA index - 14, 2495
• 양식: lyophilized
• 효능: ≤20 μg/mL lectin agglutination activity (as determined from serial dilutions of a 1 mg/mL solution)
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze
• pI: 4.5 - 5.5
• 저장 온도: 2-8°C

설명

일반 설명

Carbohydrate-binding protein that agglutinates various animal cells. Also known to restore the growth pattern of tumor cells to that of normal cells. T lymphocyte activator. Has binding sites for metal ions, α-D-mannose, and α-D-glucose. Has a pI of 4.5-5.5.

경고

Toxicity: Harmful (C)

제조 메모

To dissolve, add Con A slowly to a solution of 10 mM HEPES buffered saline, 100 µM CaCl₂, pH 8.5. Allow the lectin to dissolve without agitation.

재구성

Following reconstitution, aliquot and freeze (-20°C) or add 0.08% NaN₃ and refrigerate (4°C). Stock solutions are stable for up to 6 months at -20°C or for up to 3 months at 4°C.

분석 메모

The agglutination activity is the lowest conc. to agglutinate a 2% suspension of human erythrocytes after 1 hr incubation at 25°C; requires type A human blood.

기타 정보

Gantner, F., et al. 1995. Hepatology 21, 190.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H317,H334,H361
• 예방조치 성명서: P201 - P202 - P280 - P302 + P352 - P304 + P340 + P312 - P308 + P313
• Hazard Classifications: Repr. 2 - Resp. Sens. 1 - Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable