219399

Cathepsin D Substrate I

Useful as a substrate for the determination of cathepsin D activity.

• 동의어(들): Cathepsin D Substrate I, Bz-RGFFP-4-MeOβNA, HCl
• 실험식(Hill 표기법): C₄₉H₅₅N₉O₇ · xHCl
• Molecular Weight: 882.02 (free base basis)
• UNSPSC 코드: 51111800
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥95% (HPLC)
• 형태: lyophilized solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; desiccated; protect from light
• 색상: white
• solubility: DMSO: 5 mg/mL
• 형광: λ_ex ~345 nm; λ_em ~425 nm
• 배송 상태: ambient
• 저장 온도: −20°C

설명

일반 설명

A useful substrate for colorimetric or fluorometric assay of cathepsin D activity. Cathepsin D hydrolyzes the Phe-Phe bond. Dipeptidyl aminopeptidase II is required to free the 4-methoxy-β-naphthylamine (4MβNA). Excitation max: ~345 nm; emission max: ~425 nm.

Useful as a substrate for the determination of cathepsin D activity. Suitable for either colorimetric or fluorometric assay. Cathepsin D hydrolyzes the Phe-Phe bond. Requires dipeptidyl aminopeptidase II to free 4-methoxy-β-naphthylamine (4MeOβNA).

생화학적/생리학적 작용

Cell permeable: no

Primary Target
Substrate for the determination of cathepsin D activity

Product does not compete with ATP.

Reversible: no

경고

Toxicity: Standard Handling (A)

서열

Bz-Arg-Gly-Phe-Phe-Pro-4MeOβNA, HCl

기타 정보

Takahashi, T., and Tang, J. 1981. Methods Enzymol.80, 565.
Smith, R.E., and Van Frank, R.M. 1975. in Lysosomes in Biology and Pathology4 (Dingle, J.T., and Dean, R.T., eds.) p. 193, American Elsevier, Holland.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable