205548

Caffeine

Trimethylated xanthine that acts as a potent central nervous system stimulant.

• 동의어(들): Caffeine, 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
• 실험식(Hill 표기법): C₈H₁₀N₄O₂
• CAS Number: 58-08-2
• Molecular Weight: 194.19
• MDL number: MFCD00005758
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥99% (HPLC)
• 형태: solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze
• 색상: white
• solubility: chloroform: 50 mg/mL
• 배송 상태: ambient
• 저장 온도: 10-30°C
• InChI: 1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3
• InChI key: RYYVLZVUVIJVGH-UHFFFAOYSA-N

설명

일반 설명

Trimethylated xanthine that acts as a potent central nervous system stimulant. A nonselective phosphodiesterase inhibitor. At higher doses, produces tachycardia and interferes with the uptake and storage of Ca²⁺ by the sarcoplasmic reticulum in skeletal muscle. Prevents apoptosis and cell cycle effects induced by camptothecin and topotecan in HL-60 cells.

Trimethylated xanthine that acts as a potent central nervous system stimulant. At higher doses, produces tachycardia and interferes with the uptake and storage of Ca²⁺ by the sarcoplasmic reticulum in skeletal muscle. Prevents apoptosis and cell cycle effects induced by Camptothecin (Cat. No. 208925) and topotecan in HL-60 cells.

생화학적/생리학적 작용

Cell permeable: no

Primary Target
Potent central nervous system stimulant

Product does not compete with ATP.

Reversible: no

경고

Toxicity: Harmful (C)

재구성

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

기타 정보

Zhen, W., and Vaugha, A. T. 1995. Radiat. Res.141, 170.
Howell, L. L. 1993. Cancer Res.54, 4993.
Traganos, F., et al. 1993. Cancer Res.53, 4613.
Zahradnik, I., and Palade, P. 1993. Pflugers Arch. 424, 129.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1