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Merck
모든 사진(1)

주요 문서

17-283

Sigma-Aldrich

Rac1 Activation Assay Kit

Non-radioactive Rac1 Activation Assay Kit can be used to precipitate Rac1-GTP from cell lysates & detection by a Rac1 specific monoclonal antibody.

동의어(들):

Activation Assay Kit, Rac1 Activity Kit, Rac1 Assay Kit

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About This Item

UNSPSC 코드:
12161503
eCl@ss:
32161000
NACRES:
NA.32

Quality Level

종 반응성

human, rat, mouse

제조업체/상표

Upstate®

기술

activity assay: suitable
affinity binding assay: suitable

UniProt 수납 번호

배송 상태

dry ice

유전자 정보

human ... RAC1(5879)

일반 설명

Non-radioactive Rac1 Activation Assay Kit can be used to precipitate Ras-related C3 botulinum toxin substrate 1 (Rac1)-GTP from cell lysates and detected by a Rac1 specific monoclonal antibody. Rac1 belongs to the Ras superfamily of small guanosine triphosphatases (GTPases). It is expressed in two major forms such as an inactive GDP-bound form and an active GTP-bound form. Rac1 is involved in influencing several physiological conditions by interacting with effectors that activate several signaling cascades. The RAC1 gene is located on the human chromosome at 7p22.1.

애플리케이션

Rac1 Activation Assay Kit has been used in the detection of active Ras-related C3 botulinum toxin substrate 1 (Rac1) in brain homogenates of mice and humans by immunoblotting.

성분

Anti-Rac1, clone 23A8 (Cat.# 05-389)

Mg2+ Lysis/Wash Buffer, 5X (Cat.# 20-168)

100X GTPγS, 10mM (Cat.# 20-176)

100X GDP, 100mM (Cat.# 20-177)

Rac/cdc42 Assay Reagent (PAK1 PBD, agarose) (Cat.# 14-325)

품질

Routinely evaluated by precipitating Rac-GTP from 3T3 cell lysates that had been loaded with GTPγS. The precipitated Rac-GTP was detected by immunoblot analysis using anti-Rac.

결합

Replaces: SGT425

법적 정보

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

픽토그램

CorrosionEnvironment

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1

Storage Class Code

10 - Combustible liquids


시험 성적서(COA)

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문서 라이브러리 방문

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Annals of the Academy of Medicine, Singapore, 19, 67-72 (1990)
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