1.07185

Pepsin

(from porcine gastric mucosa) 0.7 FIP-U/mg for biochemistry EC 3.4.23.1

• 동의어(들): Pepsin
• CAS Number: 9001-75-6
• Molecular Weight: 35000
• MDL number: MFCD00081840
• UNSPSC 코드: 12352204
• EC 인덱스 번호: 232-629-3
• NACRES: NA.21

속성

• pH: 4.0-5.0 (20 °C, 10 g/L in H₂O)
• solubility: 10 g/L
• 벌크 밀도: 380‑420 kg/m³
• 저장 온도: 2-30°C

설명

애플리케이션

Pepsin has been used in the preparation of simulated gastric fluid to perform in vitro gastric digestion.

생화학적/생리학적 작용

Pepsin is a component of gastric juice and is associated with protein digestion. It is an endopeptidase that catalyzes the degradation of proteins into peptides and amino acids for small intestinal absorption. Pepsin is released as a zymogen (pepsinogen) by the chief cells of the gastric lining. It gets activated by the acidic environment created by the hydrochloric acid (HCl) of gastric juice. Pepsin is active at pH 1.5 to 2, in the stomach. It is involved in the conversion of food bolus into chyme. It is associated with laryngopharyngeal reflux (LPR) indicated by chronic cough, mild dysphagia, hoarseness, and non-productive throat clearing.

분석 메모

Appearance: fine, slightly yellow powder
Activity/FIP (Hemoglobin; pH 1.6; 25 °C): ≥ 0.70 FIP-U/mg
pH-value (1 %; water): 4.0 - 5.0
Water (according to Karl Fischer): ≤ 6.0 %

안전성 정보

• 픽토그램: GHS07,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H315 - H319 - H334 - H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable