1.00002

Tri-n-butyl phosphate

EMPROVE^® EXPERT, Ph. Eur.

• 동의어(들): Tributyl phosphate, TBP, TBPA
• Linear Formula: (CH₃(CH₂)₃O)₃PO
• CAS Number: 126-73-8
• Molecular Weight: 266.31
• Beilstein: 1710584
• MDL number: MFCD00009436
• UNSPSC 코드: 12352303
• EC 인덱스 번호: 204-800-2

속성

• Agency: Ph. Eur.
• Quality Level: 500
• vapor density: 9.2 (vs air)
• vapor pressure: 27 mmHg ( 178 °C); 7.3 mmHg ( 150 °C)
• 제품 라인: EMPROVE^® EXPERT
• 형태: liquid
• autoignition temp.: 770 °F
• refractive index: n20/D 1.424 (lit.)
• bp: 180-183 °C/22 mmHg (lit.)
• mp: −79 °C (lit.)
• 전이 온도: flash point 146 °C
• solubility: 6 g/L
• density: 0.979 g/mL at 25 °C (lit.)
• 응용 분야: liquid formulation; pharma/biopharma processes; pharmaceutical
• 저장 온도: 15-25°C
• SMILES string: CCCCOP(=O)(OCCCC)OCCCC
• InChI: 1S/C12H27O4P/c1-4-7-10-14-17(13,15-11-8-5-2)16-12-9-6-3/h4-12H2,1-3H3
• InChI key: STCOOQWBFONSKY-UHFFFAOYSA-N

설명

일반 설명

Chemicals play an important role in the stabilization of a biologic drug during its manufacturing and formulation process – for instance, by preventing aggregation. We offer a wide range of high-quality stabilizers, buffers and salts to successfully purify and formulate your biomolecules. Specifically developed for high-risk applications, they are low in bioburden and endotoxins.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

애플리케이션

Tri-n-butyl phosphate is used widely as a solvent along with either TritonTM X100 or Tween^® in solvent detergent treatment for viral inactivation procedures especially for plasma derived therapeutics.
Due to its low microbial and endotoxin limits, Tri-n-butyl phosphate Emprove^® Expert is especially suitable for high-risk applications.

법적 정보

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

TWEEN is a registered trademark of Croda International PLC

안전성 정보

• 픽토그램: GHS08,GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302,H315,H351,H412
• 예방조치 성명서: P202 - P264 - P273 - P301 + P312 - P302 + P352 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Skin Irrit. 2
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): 293.0 °F - closed cup
• Flash Point (°C): 145 °C - closed cup