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Merck
모든 사진(1)

Key Documents

07-681

Sigma-Aldrich

Anti-phospho-AMPK α (Thr172) Antibody

Upstate®, from rabbit

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

항체 형태

purified immunoglobulin

항체 생산 유형

primary antibodies

클론

polyclonal

종 반응성

human, rat

제조업체/상표

Upstate®

기술

western blot: suitable

동형

IgG

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

타겟 번역 후 변형

phosphorylation (pThr172)

유전자 정보

human ... PRKAA1(5562)

특이성

Recognizes phospho-AMPKα.

면역원

KLH-conjugated, synthetic peptide corresponding to amino acids surrounding phosphorylated Thr172 of human AMP-activated protein kinase alpha 2 (AMPKα2)

애플리케이션

Anti-phospho-AMPK α (Thr172) Antibody is an antibody against phospho-AMPK α (Thr172) for use in WB.

품질

routinely evaluated by immunoblot on RIPA lysates from overnight starved HEK293 cells and partially purified rat liver AMPK

표적 설명

Mr 63 kDa

물리적 형태

Format: Purified

분석 메모

Control
Serum starved HEK293 cells

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

법적 정보

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1


시험 성적서(COA)

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문서 라이브러리 방문

J F P Wojtaszewski et al.
Biochemical Society transactions, 31(Pt 6), 1290-1294 (2003-12-04)
The AMPK (5'AMP-activated protein kinase) is becoming recognized as a critical regulator of energy metabolism. However, many of these effects in muscle metabolism have been ascribed to AMPK based on the use of the unspecific activator AICAR (5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside). Using mouse
Roles of 5'-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis.
Rutter, Guy A, et al.
The Biochemical Journal, 375, 1-16 (2003)
Mathias Fasshauer et al.
Biochimie, 86(11), 779-784 (2004-12-14)
Several adipocyte-secreted factors have been demonstrated to potentially link obesity, insulin resistance, and cardiovascular disease. Among those, adiponectin is an insulin-sensitizing and anti-inflammatory adipokine, concentrations of which are decreased in obesity-associated metabolic and vascular disorders. Recently, two adiponectin receptors (AdipoR)
Tue L Nielsen et al.
Molecular genetics and metabolism, 123(1), 21-27 (2017-11-28)
McArdle disease (glycogen storage disease type V) is an inborn error of skeletal muscle metabolism, which affects glycogen phosphorylase (myophosphorylase) activity leading to an inability to break down glycogen. Patients with McArdle disease are exercise intolerant, as muscle glycogen-derived glucose
Enhanced external counterpulsation improves peripheral artery function and glucose tolerance in subjects with abnormal glucose tolerance.
Martin, JS; Beck, DT; Aranda, JM; Braith, RW
Journal of Applied Physiology (1985)

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