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Merck
모든 사진(1)

Key Documents

05-636-AF488

Sigma-Aldrich

Anti-phospho Histone H2A.X (Ser139), clone JBW301, Alexa Fluor 488 Conjugate Antibody

clone JBW301, from mouse, ALEXA FLUOR 488

동의어(들):

Histone H2AX, H2a/x, Histone H2A.X

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

mouse

Quality Level

결합

ALEXA FLUOR 488

항체 형태

purified antibody

항체 생산 유형

primary antibodies

클론

JBW301, monoclonal

종 반응성

human

종 반응성(상동성에 의해 예측)

vertebrates (based on 100% sequence homology)

기술

immunocytochemistry: suitable

동형

IgG1

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

타겟 번역 후 변형

phosphorylation (pSer139)

유전자 정보

human ... H2AX(3014)

일반 설명

Histone H2A.X is a variant of histone H2A, and is similarly associated with genomic DNA. However, histone is structurally different from other members of the H2A family in possessing a C-terminal tail that contains the Ser139 residue that is phosphorylated in response to breaks in double-stranded DNA. The phosphorylation of H2A.X is a rapid process that is mediated by ATM/ATR proteins.

애플리케이션

This Anti-phospho Histone H2A.X (Ser139) antibody, clone JBW301, Alexa Fluor 488 Conjugate is validated for use in ICC for the detection of phospho Histone H2A.X (Ser139).

품질

Evaluated by Immunocytochemistry in untreated (negative control) and Staurosporin treated HeLa cells.

Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected phospho-Histone H2A.X (Ser139) in Staurosporin treated HeLa cells, and not in untreated HeLa cells.

표적 설명

17 kDa calculated

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

법적 정보

ALEXA FLUOR is a trademark of Life Technologies

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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