추천 제품
Quality Level
사용
kit sufficient for 96 wells
종 반응성
human
제조업체/상표
SMC®
파라미터
25 μL sample volume (CSF)
50 μL sample volume (serum and plasma)
assay range
intra-assay cv: ≤10%
(n=3)
sensitivity: 0.87 pg/mL
standard curve range: 0.43-1500 pg/mL
linearity: 80-120%
recovery range: 80-120%
inter-assay cv: ≤11%
(n=3)
기술
single molecule counting: suitable
입력
plasma (K2 EDTA)
cerebrospinal fluid (CSF)
serum
배송 상태
wet ice
저장 온도
2-8°C
일반 설명
Neurofilament Light Chain (NF-L) is a low molecular weight member of a family of proteins involved in axonal development and function. NF-L accumulation is viewed as a telltale sign of axonal damage in the brain, and is a key marker in a wide range of neurodegenerative diseases, especially as a blood-based biomarker. We are proud to aid these efforts by offering the new SMC® Human NF-L High Sensitivity Immunoassay Kit. By coupling this assay with the powerful state-of-the-art SMCxPRO® detection system, researchers can accurately assess NF-L concentrations even in low abundance in human serum, plasma, and CSF samples, enabling studies that examine the relevance of this key analyte from health to disease.
Research Category:
Neuroscience
Neurological
Research Sub-Category:
Alzheimer′s Disease
Aging
Nervous System
Neurodegenerative Diseases
Neurofilament & Neuron Metabolism
Neuronal & Glial Markers
Neuroregenerative Medicine
Neuroscience
Research Category:
Neuroscience
Neurological
Research Sub-Category:
Alzheimer′s Disease
Aging
Nervous System
Neurodegenerative Diseases
Neurofilament & Neuron Metabolism
Neuronal & Glial Markers
Neuroregenerative Medicine
Neuroscience
특이성
This assay was tested for cross-reactivity with Neurofilament Medium Chain (NF-M), Neurofilament Heavy Chain (NF-H), phospho-Tau (T181), total Tau, and Glial Fibrillary Acidic Protein (GFAP). No cross-reactivity was detected with these analytes.
애플리케이션
Used for ultrasensitivite quantification of Human NF-L in human serum, plasma, and CSF.
특징 및 장점
This SMC® kit features:
- Accurate and reproducible performance on the state-of-the-art SMCxPRO® ultrasensitive immunoassay system.
- Compatiblity with automated liquid handling
법적 정보
SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
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