T-027

cis-Tramadol hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant^®

• 실험식(Hill 표기법): C₁₆H₂₆ClNO₂
• CAS Number: 22204-88-2
• Molecular Weight: 299.84
• MDL number: MFCD03701237
• UNSPSC 코드: 41116107
• PubChem Substance ID: 329826599
• NACRES: NA.24

속성

• Grade: certified reference material
• Quality Level: 300
• 양식: liquid
• 특징: Snap-N-Spike^®/Snap-N-Shoot^®
• 포장: ampule of 1 mL
• 제조업체/상표: Cerilliant^®
• 농도: 1.0 mg/mL in methanol (as free base)
• 기술: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 응용 분야: forensics and toxicology
• 형식: single component solution
• 저장 온도: −20°C
• SMILES string: Cl.COc1cccc(c1)[C@@]2(O)CCCC[C@@H]2CN(C)C
• InChI: 1S/C16H25NO2.ClH/c1-17(2)12-14-7-4-5-10-16(14,18)13-8-6-9-15(11-13)19-3;/h6,8-9,11,14,18H,4-5,7,10,12H2,1-3H3;1H/t14-,16+;/m1./s1
• InChI key: PPKXEPBICJTCRU-XMZRARIVSA-N

설명

일반 설명

This certified solution standard is suitable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications from forensic analysis and clinical toxicology to urine drug testing and pharmaceutical research. Tramadol is a synthetic analgesic used to treat moderate to moderately severe pain. The drug has a wide range of applications from treatment of rheumatoid arthritis to fibromyalgia.

애플리케이션

• Enantiomeric Analysis in Pharmacokinetics: A study detailed the quantitation of tramadol and its metabolites, including the enantiomers, in human whole blood using liquid chromatography-mass spectrometry (LC-MS/MS). This research is vital for understanding the pharmacokinetics of cis-Tramadol, supporting its application in pain management and enhancing the accuracy of pharmaceutical research in analgesic efficacy and safety (Haage et al., 2016).


• Psychoactive Drug Detection: Another study developed a multicomponent LC-MS/MS screening method for the detection of new psychoactive substances, including tramadol, in urine. This method is crucial for forensic and clinical toxicology, providing insights into the abuse potential of substances like cis-Tramadol and aiding in the regulatory monitoring of controlled substances (Al-Saffar et al., 2013).

법적 정보

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS02,GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H225,H301 + H311 + H331,H370
• 예방조치 성명서: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 표적 기관: Eyes,Central nervous system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point (°F): 49.5 °F - closed cup
• Flash Point (°C): 9.7 °C - closed cup