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Merck
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L-907

Supelco

Lormetazepam solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C16H12Cl2N2O2
CAS Number:
848-75-9
Molecular Weight:
335.18
EC Number:
200-659-6
MDL number:
MFCD00058578
UNSPSC 코드:
41116107
PubChem Substance ID:
329817667
NACRES:
NA.24

Grade

certified reference material

Quality Level

300

양식

liquid

특징

Snap-N-Spike®/Snap-N-Shoot®

포장

ampule of 1 mL

제조업체/상표

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

농도

1.0 mg/mL in methanol

기술

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

응용 분야

clinical testing

형식

single component solution

저장 온도

−20°C

SMILES string

CN1C(=O)C(O)N=C(c2ccccc2Cl)c3cc(Cl)ccc13

InChI

1S/C16H12Cl2N2O2/c1-20-13-7-6-9(17)8-11(13)14(19-15(21)16(20)22)10-4-2-3-5-12(10)18/h2-8,15,21H,1H3

InChI key

FJIKWRGCXUCUIG-UHFFFAOYSA-N

일반 설명

Lormetazepam is a benzodiazepine with sedative-hypnotic, anxiolytic, anticonvulsant, and muscle relaxant effects. This certified solution standard is suitable for use in LC/MS or GC/MS applications for urine drug testing, clinical toxicology, and forensic analysis. Lormetazepam is sold under trade names Loramet and Noctamid for treatment of insomnia.

법적 정보

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

픽토그램

FlameSkull and crossbonesHealth hazard
GHS02,GHS06,GHS08

신호어

Danger

유해 및 위험 성명서

H225,H301 + H311 + H331,H370

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

표적 기관

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point (°F)

49.5 °F - closed cup

Flash Point (°C)

9.7 °C - closed cup

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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Hervé Allain et al.
European journal of clinical pharmacology, 59(3), 179-188 (2003-05-21)
In elderly patients, both falls and impaired memory are considerable medical problems. Hypnotics, which are frequently administered to this patient group for the treatment of insomnia, should ideally not impair equilibrium or memory functions. This double-blind, randomised, four-way, cross-over study
Francesco Benedetti et al.
International clinical psychopharmacology, 19(5), 311-317 (2004-08-04)
Benzodiazepines can shift the phase of circadian rhythms in mammalian species, but few data are available on their phase-response effects in humans, and on possible links between timing of administration and hypnotic efficacy. Using a placebo-controlled, cross-over design, we evaluated
Inga Katofsky et al.
Sleep medicine, 13(5), 463-468 (2012-02-22)
This study was conducted to evaluate the effectiveness of a cognitive behavioral self-help program (SHP) in combination with pharmacotherapy in patients with primary insomnia in general practice. Patients were recruited from 31 general practitioners (GPs) in the Hamburg area, who
E Nováková
Soudni lekarstvi, 43(1), 2-4 (1998-04-30)
The determination of benzodiazepine derivatives lorazepam and lormetazepam in urine is based on detection of their metabolites 2-amino-2',5-dichlorobenzophenone and 2-methylamino-2'5-dichlorbenzophenone in hydrolyzed urine. Both substances are structurally very similar to the metabolites of diazepam 2-amino-5-chlorbenzophenone and 2-methylamino-5-chlorbenzophenone and their mobility
Patrick Lemmer et al.
Journal of analytical toxicology, 31(4), 224-226 (2007-06-09)
Lormetazepam (Loramet is a benzodiazepine mainly used as an hypnotic to treat insomnia. Lorazepam (Temesta) is used as an anxiolytic, tranquilizer, sedative, and anticonvulsant, and it is the major metabolite of lormetazepam. In this study, we designed a method to
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