추천 제품
Grade
analytical standard
Quality Level
포장
vial of 25 mg
제조업체/상표
Cerilliant®
응용 분야
environmental
forensics and toxicology
형식
neat
저장 온도
room temp
SMILES string
c1ccc2c(c1)cc3ccc4cccc5c6ccccc6c2c3c45
InChI
1S/C24H14/c1-2-8-18-16(6-1)14-17-13-12-15-7-5-11-20-19-9-3-4-10-21(19)24(18)23(17)22(15)20/h1-14H
InChI key
JNTHRSHGARDABO-UHFFFAOYSA-N
유사한 제품을 찾으십니까? 방문 제품 비교 안내
일반 설명
Dibenzo[a,l]pyrene is a polycyclic aromatic hydrocarbon (PAH) found in cigarette smoke condensate and coal combustion. It is an environmental pollutant and a potent carcinogen known to induce tumors in rat mammary gland, mouse skin, lungs and liver.
애플리케이션
Dibenzo[a,l]pyrene may be used as an analytical standard for the determination of the analyte in crude extracts of environmental samples, water samples and Chinese coal fly ash CRM by chromatography and spectrometry techniques.
법적 정보
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Carc. 1B - Eye Dam. 1 - Muta. 2
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
가장 최신 버전 중 하나를 선택하세요:
Direct determination of dibenzo [a, l] pyrene in crude extracts of environmental samples by laser-excited Shpol'skii spectroscopy
Kozin IS, et al.
Analytical Chemistry, 67(9), 1623-1626 (1995)
Fredine T Lauer et al.
Journal of toxicology and environmental health. Part A, 76(1), 16-24 (2012-11-16)
Dibenzo[def,p]chrysene (DBC) is a potent environmental carcinogen in rodents, fish, and human cells examined in culture. There are numerous similarities between the patterns of cytochrome P-450 (P450) activation of DBC and its covalent binding to DNA and proteins with another
Susan Ritger Crowell et al.
Toxicology and applied pharmacology, 257(3), 365-376 (2011-10-18)
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants generated as byproducts of natural and anthropogenic combustion processes. Despite significant public health concern, physiologically based pharmacokinetic (PBPK) modeling efforts for PAHs have so far been limited to naphthalene, plus simpler PK
Kun-Ming Chen et al.
International journal of cancer, 133(6), 1300-1309 (2013-03-14)
We previously reported that dibenzo[a,l]pyrene (DB[a,l]P), the most potent known environmental carcinogen among polycyclic aromatic hydrocarbons (PAH) congeners, is carcinogenic in the oral tissues of mice. We have now developed a new mouse model which employs the oral application of
Yijin Tang et al.
Biochemistry, 51(48), 9751-9762 (2012-11-06)
The most potent tumorigen identified among the polycyclic aromatic hydrocarbons (PAH) is the nonplanar fjord region dibenzo[a,l]pyrene (DB[a,l]P). It is metabolically activated in vivo through the widely studied diol epoxide (DE) pathway to form covalent adducts with DNA bases, predominantly
Global Trade Item Number
SKU | GTIN |
---|---|
ERD-051-25MG | 4061833609651 |
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