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Merck
모든 사진(1)

주요 문서

D-067

Supelco

Digitoxin solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

로그인조직 및 계약 가격 보기


About This Item

실험식(Hill 표기법):
C41H64O13
CAS Number:
Molecular Weight:
764.94
UNSPSC 코드:
41116107
NACRES:
NA.24

Grade

certified reference material

Quality Level

형태

liquid

특징

Snap-N-Spike®/Snap-N-Shoot®

포장

ampule of 1 mL

제조업체/상표

Cerilliant®

농도

1.0 mg/mL in methanol

기술

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

응용 분야

pharmaceutical (small molecule)

형식

single component solution

저장 온도

−20°C

SMILES string

CC1OC(CC(O)C1O)OC2C(O)CC(OC2C)OC3C(O)CC(OC3C)OC4CCC5(C)C(CCC6C5CCC7(C)C(CCC67O)C8=CC(=O)OC8)C4

InChI

1S/C41H64O13/c1-20-36(46)29(42)16-34(49-20)53-38-22(3)51-35(18-31(38)44)54-37-21(2)50-33(17-30(37)43)52-25-8-11-39(4)24(15-25)6-7-28-27(39)9-12-40(5)26(10-13-41(28,40)47)23-14-32(45)48-19-23/h14,20-22,24-31,33-38,42-44,46-47H,6-13,15-19H2,1-5H3

InChI key

WDJUZGPOPHTGOT-UHFFFAOYSA-N

일반 설명

A cardiac glycoside and antiarrhythmic drug similar in structure and effect to digoxin. Digitoxin is monitored by clinical labs to ensure patients remain within the drug′s therapeutic range.

법적 정보

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

픽토그램

FlameSkull and crossbonesHealth hazard

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

표적 기관

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point (°F)

49.5 °F - closed cup

Flash Point (°C)

9.7 °C - closed cup


시험 성적서(COA)

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문서 라이브러리 방문

이미 열람한 고객

Erik S Anderson et al.
RNA (New York, N.Y.), 18(5), 1041-1049 (2012-03-30)
Modulation of alternative pre-mRNA splicing is a potential approach to therapeutic targeting for a variety of human diseases. We investigated the mechanism by which digitoxin, a member of the cardiotonic steroid class of drugs, regulates alternative splicing. Transcriptome-wide analysis identified
Beneficial effect of digitoxin for heart failure from noncompaction in myotonic dystrophy 1.
Josef Finsterer et al.
International journal of cardiology, 160(3), e50-e51 (2012-04-06)
[Do we still need digitalis today?].
E Erdmann
MMW Fortschritte der Medizin, 152(6), 18-18 (2010-03-23)
Digitalis and diabetes.
Steinar Madsen
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 132(9), 1105-1105 (2012-05-23)
Helene Hallböök et al.
PloS one, 6(1), e15718-e15718 (2011-01-20)
Despite years of interest in the anti-cancerous effects of cardiac glycosides (CGs), and numerous studies in vitro and in animals, it has not yet been possible to utilize this potential clinically. Reports have demonstrated promising in vitro effects on different

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