추천 제품
양식
liquid
포장
pkg of 1 × 1 mL (880123X-500ug)
제조업체/상표
Avanti Research™ - A Croda Brand 880123X
농도
0.5 mg/mL (880123X-500ug)
배송 상태
dry ice
저장 온도
−20°C
SMILES string
[H][C@@](COP([O-])(OCCNC([(OCH2CH2)113]NC(CC[C@H](NC(C1=CC=C(NCC(C=N2)=NC3=C2N=C(N)NC3=O)C=C1)=O)C([O-])=O)=O)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+]
일반 설명
DSPE-PEG(5000) Folate(1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate(polyethylene glycol)-5000]) is incorporated into liposomes as a targeting ligand for folate receptors, which acts as cellular surface markers for various cancers and myeloid leukemias. Folate targeted drug delivery is potentially used for the treatment and imaging of several cancers and inflammatory diseases. Folate conjugates are small molecules having high binding affinity for folate receptors (FR) on cell surface. Therefore, they have an ability to deliver a variety of molecular complexes to pathologic cells without affecting normal tissues.
애플리케이션
DSPE-PEG(5000) Folate may be used:
- in preparation of folate functionalized nanoparticles (NPs)
- in synthesis of BTPEPBI-containing nanoparticles
- in preparation of paclitaxel loaded folate modified lipid-shell and polymer-core nanoparticles (FLPNPs)
포장
5 mL Clear Glass Sealed Ampule (880123X-500ug)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
신호어
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 1 - STOT SE 3
표적 기관
Central nervous system
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Folate-modified lipid--polymer hybrid nanoparticles for targeted paclitaxel delivery
Zhang L, et al.
International journal of nanomedicine, 10, 2101-2101 (2015)
Linhua Zhang et al.
International journal of nanomedicine, 10, 2101-2114 (2015-04-07)
The purpose of this study was to develop a novel lipid-polymer hybrid drug carrier comprised of folate (FA) modified lipid-shell and polymer-core nanoparticles (FLPNPs) for sustained, controlled, and targeted delivery of paclitaxel (PTX). The core-shell NPs consist of 1) a
Aggregation-induced red-NIR emission organic nanoparticles as effective and photostable fluorescent probes for bioimaging
Zhao Q, et al.
Journal of Materials Chemistry, 22(30), 15128-15135 (2012)
Zhaoyan Yang et al.
ACS applied materials & interfaces, 11(51), 47671-47679 (2019-10-22)
Lead halide perovskite nanocrystals (NCs) are promising optical materials in many fields. However, their poor moisture stability, significant toxicity, and difficulty to be further functionalized greatly hinder their applications in bioimaging. Here, a universal strategy is demonstrated by simply encapsulating
Folate receptor-mediated drug targeting: from therapeutics to diagnostics
Hilgenbrink AR and Low PS
Journal of Pharmaceutical Sciences, 94(10), 2135-2146 (2005)
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