860074W

C18:0 GM3 (synthetic)

Avanti Research^™ - A Croda Brand 860074W, methanol solution

• 동의어(들): C18:0 GM3 Ganglioside (synthetic, ammonium salt)
• 실험식(Hill 표기법): C₅₉H₁₁₁N₃O₂₁
• CAS Number: 1246353-19-4
• Molecular Weight: 1198.52
• UNSPSC 코드: 12352211
• NACRES: NA.25

속성

• 분석: >99% (TLC)
• 양식: methanol solution
• 포장: pkg of 1 × 1 mL (860074W-100ug)
• 제조업체/상표: Avanti Research^™ - A Croda Brand 860074W
• 농도: 0.1 mg/mL (860074W-100ug)
• 지질 유형: sphingolipids; cardiolipins
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: [H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)CO[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@@H]([C@H](O[C@@]3(C([O-])=O)O[C@@H]([C@H](O)[C@H](O)CO)[C@@](NC(C)=O)([H])[C@@H](O)C3)[C@H]2O)O)[C@@H](CO)O1.[NH4+]
• InChI: 1S/C59H108N2O21.H3N/c1-4-6-8-10-12-14-16-18-19-21-23-25-27-29-31-33-46(69)61-40(41(66)32-30-28-26-24-22-20-17-15-13-11-9-7-5-2)38-77-56-51(73)50(72)53(45(37-64)79-56)80-57-52(74)55(49(71)44(36-63)78-57)82-59(58(75)76)34-42(67)47(60-39(3)65)54(81-59)48(70)
• InChI key: WFQOHDPRXSLGNK-BLVJLEROSA-N

설명

일반 설명

Ganglioside monosialodihexosylganglioside (GM3) are membrane-bound glycosphingolipids (GSLs). It comprises a sialic acid residue and an oligosaccharide head structure. GM3 is present in milk and kidney cells. GM3 is the most widely present ganglioside in tissues.

생화학적/생리학적 작용

Ganglioside monosialodihexosylganglioside (GM3) modulates apoptosis, cell proliferation and differentiation. It is also essential for cellular signaling pathways, cell adhesion and mobility. GM3 prevents the action of fibroblast growth factor receptor. Low levels of ganglioside GM3 is associated with the pathogenesis of rheumatoid arthritis. GM3 maintains immunological functions by inhibiting cytokine production.

포장

2 mL Amber Glass Sealed Ampule (860074W-100ug)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• 픽토그램: GHS02,GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H225,H301 + H311 + H331,H370
• 예방조치 성명서: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 표적 기관: Eyes
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point (°F): 49.5 °F - closed cup
• Flash Point (°C): 9.7 °C - closed cup