860053P

Ganglioside-Total

Avanti Research^™ - A Croda Brand

• 동의어(들): Total Ganglioside Extract (Brain, Porcine-Ammonium Salt)
• CAS Number: 383907-71-9
• UNSPSC 코드: 12352211
• NACRES: NA.25

속성

• 분석: >99% (TLC)
• 형태: powder
• 포장: pkg of 1 × 10 mg (860053P-10mg); pkg of 1 × 25 mg (860053P-25mg); pkg of 1 × 50 mg (860053P-50mg)
• 제조업체/상표: Avanti Research^™ - A Croda Brand
• 지질 유형: sphingolipids
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: [H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)CO[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@@H]([C@H](O[C@@]3(C([O-])=O)O[C@@H]([C@H](O)[C@H](O)CO)[C@@](NC(C)=O)([H])[C@@H](O)C3)[C@H]2O)O[C@@H]4O[C@H](CO)[C@@H]([C@H](O[C@@H]5O[C@H

설명

일반 설명

Gangliosides are glycosphingolipids, that contain sialic acid residues in the glycan chain. They are mainly present on the surface of neuronal cells. Gangliosides are also present in serum. Four complex ganglioside structures, such as GM1, GD1a, GD1b and GT1b are the most abundantly found ganglioside in mammalian brains. Gangliosides comprise a ceramide tail attached to a polar carbohydrate head.

애플리케이션

Ganglioside-Total may be used:

• as a standard to investigate the efficiency of ganglioside extraction in brain using electrospray ionization-mass spectrometry (ESI MS) analysis
• as a hemagglutinin (HA) binding receptor to assemble nanodisc with affinity to influenza virus (NDTG) and also to determine the effect of total ganglioside extract (TG) amount on total ganglioside
• in liposomes to measure ostreolysin A (OlyA) binding in order to deduce the effects of phosphatidylcholines (PCs) on sphingomyelin

생화학적/생리학적 작용

Gangliosides regulate various biological activities in cell plasma membranes (PMs). It provides structural rigidity to the cell. Ganglioside clusters form membrane microdomains, which facilitates cell adhesion. It also functions as differentiating markers during oncogenesis, embryogenesis, lymphoid differentiation and neoplastic transformation. Gangliosides have the ability to repress cell-mediated immune functions. It is also associated with cancer and Alzheimer′s disease.

포장

5 mL Amber Glass Screw Cap Vial (860053P-10mg)

5 mL Amber Glass Screw Cap Vial (860053P-25mg)

5 mL Amber Glass Screw Cap Vial (860053P-50mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): No data available
• Flash Point (°C): No data available