분석
>99% (BMP (contains 30% positional isomers), TLC)
형태
powder
포장
pkg of 1 × 5 mg (857136P-5mg)
제조업체/상표
Avanti Research™ - A Croda Brand 857136P
지질 유형
phospholipids
cardiolipins
배송 상태
dry ice
저장 온도
−20°C
SMILES string
[H][C@@](COP(OC[C@]([H])(O)COC(CCCCCCC/C=C\CCCCCCCC)=O)([O-])=O)(O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+]
일반 설명
Bis(monoacylglycerol)phosphate (BMP) is an acidic phospholipid. It is mostly located in the lysosomal and endosomal compartments within cells.
생화학적/생리학적 작용
Bis(monoacylglycerol)phosphate (BMP) regulates late endosomes/lysosomes (LE/Lys) degradation pathway. It also modulates cholesterol homeostasis and trafficking of lysosomal enzymes. BMP is implicated in the digestion and recycling of membranous materials and synthesis of intra luminal vesicles.
포장
5 mL Clear Glass Sealed Ampule (857136P-5mg)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Ion mobility and tandem mass spectrometry of phosphatidylglycerol and bis (monoacylglycerol) phosphate (BMP)
International Journal of Mass Spectrometry, 378, 255-263 (2015)
Toxicology and applied pharmacology, 279(3), 467-476 (2014-06-27)
The inability to routinely monitor drug-induced phospholipidosis (DIPL) presents a challenge in pharmaceutical drug development and in the clinic. Several nonclinical studies have shown di-docosahexaenoyl (22:6) bis(monoacylglycerol) phosphate (di-22:6-BMP) to be a reliable biomarker of tissue DIPL that can be
PLoS pathogens, 6(10), e1001131-e1001131 (2010-10-16)
Many enveloped viruses invade cells via endocytosis and use different environmental factors as triggers for virus-endosome fusion that delivers viral genome into cytosol. Intriguingly, dengue virus (DEN), the most prevalent mosquito-borne virus that infects up to 100 million people each
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