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Merck
모든 사진(2)

주요 문서

840506C

Avanti

18:0-22:6 PG

1-stearoyl-2-docosahexaenoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt), chloroform

동의어(들):

1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); PG(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)); 110655

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About This Item

실험식(Hill 표기법):
C46H78O10PNa
CAS Number:
Molecular Weight:
845.07
UNSPSC 코드:
51191904
NACRES:
NA.25

분석

>99% (TLC)

양식

liquid

포장

pkg of 1 × 2.5 mL (840506C-25mg)

제조업체/상표

Avanti Research - A Croda Brand 840506C

농도

10 mg/mL (840506C-25mg)

지질 유형

cardiolipins
phospholipids

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[Na+].[P](=O)([O-])(OC[C@H](OC(=O)CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CC)COC(=O)CCCCCCCCCCCCCCCCC)OCC(O)CO

InChI

1S/C46H79O10P.Na/c1-3-5-7-9-11-13-15-17-19-20-21-22-24-26-28-30-32-34-36-38-46(50)56-44(42-55-57(51,52)54-40-43(48)39-47)41-53-45(49)37-35-33-31-29-27-25-23-18-16-14-12-10-8-6-4-2;/h5,7,11,13,17,19,21-22,26,28,32,34,43-44,47-48H,3-4,6,8-10,12,14-16,18,20,23-25,27,29-31,33,35-42H2,1-2H3,(H,51,52);/q;+1/p-1/b7-5-,13-11-,19-17-,22-21-,28-26-,34-32-;/t43?,44-;/m1./s1

InChI key

MZXILCJOOQSOIZ-DTRIVZRESA-M

일반 설명

18:0-22:6 PG or 1-stearoyl-2-docosahexaenoyl-sn-glycero-3-phospho-(1′-rac-glycerol) is a sodium salt of glycerophospholipid, with substitution of stearic acid, docosahexaenic acid and phospho-rac-(1-glycerol) at the sn-1, sn-2 and sn-3 positions respectively, in the glycerol backbone.

애플리케이션

18:0-22:6 PG or 1-stearoyl-2-docosahexaenoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt) has been used as a standard in bilayer vesicles for the systematic analysis of different oxidized phospholipid (Ox-PL) patterns by oxidation of PL vesicles using a Cu2+ solution. It has also been used in liposomes, to serve as an acidic phospholipid control and to determine the lipid-binding properties of the Praja-1 protein and also its E3 ubiquitin-protein ligase action.

포장

5 mL Clear Glass Sealed Ampule (840506C-25mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

픽토그램

Skull and crossbonesHealth hazard

신호어

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

표적 기관

Central nervous system, Liver,Kidney

WGK

WGK 3


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Oxidized low density lipoproteins (Ox-LDLs) have an important role in the development of age-related vascular disease, such as atherosclerosis. Ox-LDLs are defined as oxidatively modified LDLs in the blood by enzymatic or non-enzymatic oxidation of phospholipids (PLs). For the characterization
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FEBS letters, 594(11), 1787-1796 (2020-03-07)
Serotonin transporter (SERT) is involved in serotonergic system regulation and in the pathophysiology/therapeutics of serotonin-/SERT-related diseases such as obsessive-compulsive disorder, depression, autism, and schizophrenia. We recently revealed that diacylglycerol (DG) kinase (DGK) δ induces ubiquitination/degradation of SERT in a DGK

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