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840045X

Avanti

Brain PI(4)P

Avanti Research™ - A Croda Brand 840045X

동의어(들):

L-α-phosphatidylinositol-4-phosphate (Brain, Porcine) (ammonium Salt):methanol:water (20:9:1)

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About This Item

CAS Number:
475995-51-8
UNSPSC 코드:
12352211
NACRES:
NA.25

분석

>99% (TLC)

형태

liquid

포장

pkg of 1 × 1 mL (840045X-1mg)
pkg of 1 × 1 mL (840045X-5mg)

제조업체/상표

Avanti Research™ - A Croda Brand 840045X

농도

1 mg/mL (840045X-1mg)
5 mg/mL (840045X-5mg)

지질 유형

phosphoglycerides

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[H][C@@](COP(O[C@H]1[C@H](O)[C@@H](O)[C@H](OP(O)([O-])=O)[C@@H](O)[C@H]1O)([O-])=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+]

InChI

1S/C47H84O16P2.2H3N/c1-3-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-34-36-41(49)61-39(37-59-40(48)35-33-31-29-27-25-23-21-18-16-14-12-10-8-6-4-2)38-60-65(57,58)63-47-44(52)42(50)46(43(51)45(47)53)62-64(54,55)56;;/h11,13,17,19,22,24,28,30,39,42-47,50-53H,3-10,12,14-16,18,20-21,23,25-27,29,31-38H2,1-2H3,(H,57,58)(H2,54,55,56);2*1H3/b13-11-,19-17-,24-22-,30-28-;;/t39-,42+,43?,44?,45?,46?,47-;;/m1../s1

InChI key

HJHASIMOAXACIC-CVKYTLMISA-N

일반 설명

Phosphatidylinositol 4-phosphate (PI4P) is a precursor of phosphatidylinositol (4,5)-bisphosphate [PI(4,5)P2]. It is located in the membranes of Golgi apparatus.

애플리케이션

Brain PI(4)P has been used for molecular docking. It has also been used for the preparation of liposome for co-floatation.

포장

5 mL Clear Glass Sealed Ampule (840045X-1MG)
5 mL Clear Glass Sealed Ampule (840045X-5MG)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

픽토그램

FlameSkull and crossbonesHealth hazard
GHS02,GHS06,GHS08

신호어

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 1 - STOT SE 3

표적 기관

Central nervous system, Eyes,Central nervous system, Liver,Kidney

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point (°F)

49.5 °F

Flash Point (°C)

9.7 °C

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

The RNA-binding site of poliovirus 3C protein doubles as a phosphoinositide-binding domain
Shengjuler D, et al.
Structure, 25(12), 1875-1886 (2017)
RIM C2B domains target presynaptic active zone functions to PIP2-containing membranes
de Jong A, et al.
Neuron, 98(2), 335-349 (2018)
PI4P and PI (4, 5) P2 are essential but independent lipid determinants of membrane identity
Hammond GRV, et al.
Science, 337(6095), 727-730 (2012)
Dieter R Klopfenstein et al.
Molecular biology of the cell, 15(8), 3729-3739 (2004-05-25)
UNC-104 (KIF1A) is a kinesin motor that transports synaptic vesicles from the neuronal cell body to the terminal. Previous in vitro studies have shown that a Dictyostelium relative of UNC-104 transports liposomes containing acidic phospholipids, but whether this interaction is
Jitendra Kumar et al.
PLoS genetics, 6(11), e1001200-e1001200 (2010-11-17)
UNC-104/KIF1A is a Kinesin-3 motor that transports synaptic vesicles from the cell body towards the synapse by binding to PI(4,5)P(2) through its PH domain. The fate of the motor upon reaching the synapse is not known. We found that wild-type
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