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Key Documents

810227P

Avanti

C12-NBD Lactosyl Ceramide

Avanti Polar Lipids 810227P, powder

동의어(들):

N-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-D-lactosyl-β1-1′-sphingosine

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About This Item

실험식(Hill 표기법):
C48H81N5O16
CAS Number:
Molecular Weight:
984.18
UNSPSC 코드:
12352211
NACRES:
NA.25

분석

>99% (TLC)

형태

powder

포장

pkg of 1 × 50 μg (810227P-50ug)

제조업체/상표

Avanti Polar Lipids 810227P

배송 상태

dry ice

저장 온도

−20°C

관련 카테고리

일반 설명

C12-NBD Lactosyl ceramide is a fluorescent analog of biologically available compound lactosyl ceramide. Lactosyl ceramideis generally present on neutrophils and macrophages.

생화학적/생리학적 작용

Lactosyl ceramide is the major precursor for synthesis of various glycosphingolipids like oligoglycosylceramides and gangliosides. It is an important signaling molecule that is involved in adhesion, migration, cell proliferation and angiogenesis. Lactosyl ceramide is vital for osteoclastogenesis mediated by macrophage-colony stimulating factor.

포장

5 mL Amber Glass Screw Cap Vial (810227P-50ug)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids


시험 성적서(COA)

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문서 라이브러리 방문

T Iwamoto et al.
The Journal of biological chemistry, 276(49), 46031-46038 (2001-10-11)
Glycosphingolipids and their metabolites play important roles in a variety of biological processes. Several signal molecules are localized in a glycolipid-enriched microdomain on the cell surface, and their signals are regulated by the glycolipid composition. However, the function of glycolipids
W I Weis et al.
Annual review of biochemistry, 65, 441-473 (1996-01-01)
Lectins are responsible for cell surface sugar recognition in bacteria, animals, and plants. Examples include bacterial toxins; animal receptors that mediate cell-cell interactions, uptake of glycoconjugates, and pathogen neutralization; and plant toxins and mitogens. The structural basis for selective sugar
S Hakomori et al.
Journal of biochemistry, 118(6), 1091-1103 (1995-12-01)
Glycosphingolipids (GSLs), cell type-specific markers which change dramatically during ontogenesis and oncogenesis, have been implicated as playing major roles in cellular interactions and control of cell proliferation in multicellular organisms. These functional roles have been partially clarified through two types

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