모든 사진(1)
About This Item
실험식(Hill 표기법):
C17H25NO · HCl
CAS Number:
Molecular Weight:
295.85
MDL number:
UNSPSC 코드:
12352005
PubChem Substance ID:
NACRES:
NA.22
추천 제품
형태
solid
Quality Level
색상
white
solubility
DMSO: soluble
ethanol: soluble
SMILES string
Cl.O[C@H]1CCCC[C@@H]1N2CCC(CC2)c3ccccc3
InChI
1S/C17H25NO.ClH/c19-17-9-5-4-8-16(17)18-12-10-15(11-13-18)14-6-2-1-3-7-14;/h1-3,6-7,15-17,19H,4-5,8-13H2;1H/t16-,17-;/m0./s1
InChI key
XJNUHVMJVWOYCW-QJHJCNPRSA-N
일반 설명
D-(+)-Vesamicol is a potent inhibitor of acetycholine transport into the synaptic vesicles in cholinergic nerve terminals. It is 25-times less potent than the L-form.
애플리케이션
D-(+)-Vesamicol hydrochloride can be used as a reactant to prepare:
- Trialkylstannyl vesamicol analogs as potent vesicular acetylcholine transporters (VAChTs) and sigma receptors.
- Vesamicol analog, (+)-2-[4-(4-iodophenyl)piperidino] cyclohexanol as a possible tumor imaging agent.
생화학적/생리학적 작용
Less active enantiomer of vesamicol
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
가장 최신 버전 중 하나를 선택하세요:
A validated LC method for the determination of vesamicol enantiomers in human plasma using vancomycin chiral stationary phase and solid phase extraction.
Hefnawy MM and Aboul-Enein HY.
Journal of Pharmaceutical and Biomedical Analysis, 35(3), 535-543 (2004)
Development and evaluation of a novel radioiodinated vesamicol analog as a sigma receptor imaging agent
Ogawa K, et al.
EJNMMI Research, 2(1), 54-54 (2012)
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