추천 제품
Quality Level
분석
≥97.0%
refractive index
n20/D 1.588 (lit.)
bp
286 °C (lit.)
density
1.062 g/mL at 25 °C (lit.)
SMILES string
C1CN(CCN1)c2ccccc2
InChI
1S/C10H14N2/c1-2-4-10(5-3-1)12-8-6-11-7-9-12/h1-5,11H,6-9H2
InChI key
YZTJYBJCZXZGCT-UHFFFAOYSA-N
유전자 정보
mouse ... Htr3a(15561)
rat ... Drd2(24318) , Htr1a(24473)
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신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 2 Dermal - Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1B
Storage Class Code
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
Flash Point (°F)
284.0 °F
Flash Point (°C)
140 °C
개인 보호 장비
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Rodolfo do Couto Maia et al.
Expert opinion on therapeutic patents, 22(10), 1169-1178 (2012-09-11)
The N-phenylpiperazine subunit represents one of the most versatile scaffolds used in the medicinal chemistry field. Recently, some N-phenylpiperazine derivatives have reached late stage clinical trials for the treatment of CNS disorders, thus, this is clearly a molecular template that
Daniela Huber et al.
Bioorganic & medicinal chemistry, 20(1), 455-466 (2011-11-22)
Merging two arylamidoalkyl substituted phenylpiperazines as prototypical recognition elements for dopamine D(2)-like receptors by oligoethylene glycol linkers led to a series of bivalent ligands. These dimers were investigated in comparison to their monomeric analogues for their dopamine D(2long), D(2short), D(3)
Daniela Poli et al.
Journal of medicinal chemistry, 54(7), 2102-2113 (2011-03-16)
Following a molecular simplification approach, we have identified the 2-phenylphthalazin-1(2H)-one (PHTZ) ring system as a new decorable core skeleton for the design of novel hA(3) adenosine receptor (AR) antagonists. Interest for this new series was driven by the structural similarity
Jadwiga Handzlik et al.
Bioorganic & medicinal chemistry letters, 20(20), 6152-6156 (2010-09-04)
A series of phenylpiperazine derivatives of phenytoin was evaluated for their affinity at α(1)-adrenoceptor subtypes in functional bioassays (rat tail artery: α(1A) and/or α(1B); guinea pig spleen: α(1B); rat aorta: α(1D)). The most potent compounds at α(1A)-, α(1B)- and α(1D)-adrenoceptors
Azza A Shoukry et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 96, 586-593 (2012-08-07)
With the purpose of evaluating the ability of Pd(II) complex to interact with DNA molecule as the main biological target, two new complexes [Pd(bpy)(OH(2))(2)] (1) and [Pd(Phenpip)(OH(2))(2)] (2), where (bpy=2,2'-bipyridine; Phenpip=1-phenylpiperazine), have been synthesized and the binding properties of these
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