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Key Documents

906603

Sigma-Aldrich

DLAM-Iδ1Tγ-13CH3 Methyl Labeling Kit

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모든 사진(1)

About This Item

UNSPSC 코드:
12352200

기술

bio NMR: suitable

Quality Level

200

배송 상태

dry ice

저장 온도

−70°C

관련 카테고리

일반 설명

DLAM-Iδ1Tg-13CH3 kit has 13CH3isotopomer precursors and contains protocol instructions for creation of isotopically-labeled proteins.

애플리케이션

DLAM-Iδ1Tg-13CH3 is an optimized kit to produce proteins with 13CH3 isotopomer on the methyl groups of isoleucine and threonine. This kit has been tested with protein isotopic labeling in E. coli. It is used in methyl-TROSY NMR for the investigation of the active site of the proteasome and also in the study of catalytic mechanism.
For detection of long-range nOes or for the NMR study of large proteins

포장

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

픽토그램

Corrosion
GHS05

신호어

Danger

유해 및 위험 성명서

H314

Hazard Classifications

Skin Corr. 1B

Storage Class Code

8A - Combustible, corrosive hazardous materials

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Algirdas Velyvis et al.
Journal of the American Chemical Society, 135(25), 9259-9262 (2013-06-27)
The 20S proteasome core particle is a molecular machine that plays a central role in the regulation of cellular function through proteolysis, and it has emerged as a valuable drug target for certain classes of cancers. Central to the development
Silke Wiesner et al.
Current opinion in structural biology, 35, 60-67 (2015-09-26)
Intermolecular interactions are indispensible for biological function. Here we discuss how novel NMR techniques can provide unique insights into the assembly, dynamics and regulation of biomolecular complexes. We focus on applications that exploit the methyl TROSY effect and show that

문서

Methyl Isotope-Labeling of Proteins from NMR-Bio

Methyl groups are ideal probes for studying protein structure and function by NMR. Choose among user-friendly kits for isotope labeling of a single type or multiple types of methyl groups.

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.