900893

L-Homopropargylglycine hydrochloride

• 동의어(들): HPG
• 실험식(Hill 표기법): C₆H₉NO₂ · HCl
• CAS Number: 98891-36-2
• Molecular Weight: 163.60
• UNSPSC 코드: 12352209
• NACRES: NA.22

속성

• 양식: powder or crystals
• 재고 정보: available only in USA
• mp: 162 °C
• 저장 온도: −20°C
• SMILES string: O=C(O[H])[C@@](C([H])([H])C([H])([H])C#C[H])([H])N([H])[H].Cl[H]
• InChI: 1S/C6H9NO2/c1-2-3-4-5(7)6(8)9/h1,5H,3-4,7H2,(H,8,9)
• InChI key: SCGJGNWMYSYORS-UHFFFAOYSA-N

설명

애플리케이션

L-Homopropargylglycine (HPG) is an amino acid analog of methionine that contains a very small modification, specifically an alkyne moiety. This compound can be fed to cultured cells and incorporated into proteins during active protein synthesis. Detection utilizes the chemoselective ligation or “click” reaction between an azide and an alkyne or cyclooctyne. For example the alkyne-modified protein can be detected with either fluorescent azide or biotin azide. Detection sensitivity with these reagents in 1-D gels and Western blots is in the low femtomole range and compatible with downstream LC-MS/MS and MALDI-MS analysis.

안전성 정보

• 픽토그램: GHS02
• 신호어: Danger
• 유해 및 위험 성명서: H242
• 예방조치 성명서: P210 - P234 - P235 - P240 - P370 + P378 - P403
• Hazard Classifications: Self-react. C
• Storage Class Code: 5.2 - Organic peroxides and self-reacting hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable