802255

8-Amino-5-methoxyquinoline

95%

• 동의어(들): 5-Methoxy-8-quinolinamine, Chen Auxilliary, MQ, Gong Chen Auxiliary, MQ Auxiliary
• 실험식(Hill 표기법): C₁₀H₁₀N₂O
• CAS Number: 30465-68-0
• Molecular Weight: 174.20
• MDL number: MFCD01593679
• UNSPSC 코드: 12352100
• PubChem Substance ID: 329768733

속성

• Quality Level: 100
• 분석: 95%
• 양식: powder
• mp: 90-95 °C
• SMILES string: NC1=CC=C(OC)C2=CC=CN=C21
• InChI: 1S/C10H10N2O/c1-13-9-5-4-8(11)10-7(9)3-2-6-12-10/h2-6H,11H2,1H3
• InChI key: MFLLTRMMFHENCM-UHFFFAOYSA-N

설명

일반 설명

8-Amino-5-methoxyquinoline is a substituted quinoline derivative that can be prepared using 5-chloro-2-nitroaniline as a starting material. It can act as an easily removable directing group and also mediate C-H activation. These properties have been useful for synthesizing isomeric dibenzoxazepinones and complex pyrrolidinones from compounds containing 8-amino-5-methoxyquinoline moiety.

애플리케이션

The Chen auxiliary was reported to be an effective directing group in the synthesis of pyrrolidones from assisting in the activation of C(sp³)-H bonds and can be readily installed through amide bond formation and removed through mild conditions using CAN at room temperature.

기타 정보

Use of a Readily Removable Auxiliary Group for the Synthesis of Pyrrolidones by the Palladium-Catalyzed Intramolecular Amination of Unactivated γ C(sp³)-H bonds

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315 - H319 - H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable