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Merck
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Key Documents

793248

Sigma-Aldrich

Polyhydroxylated fullerenes, water soluble

동의어(들):

C60(OH)n, water soluble C60, Fullerenols, Polyhydroxy fullerenes

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About This Item

실험식(Hill 표기법):
C60(OH)n · mH2O (n>40, m>8)
UNSPSC 코드:
12352103
NACRES:
NA.23

형태

solid

Quality Level

색상

light yellow to yellow

solubility

water: soluble >50 mg/mL
DMSO: slightly soluble
methanol: slightly soluble

저장 온도

2-8°C

일반 설명

Polyhydroxylated fullerenes, (water soluble)(PHF) is a functionalized fullerene that is also called fullerenol which can be used as a molecular anti-oxidant and a nanoparticle. It is a non-toxic fullerene which is attached with 12-42 hydroxyl groups per molecule that result in water solubility. Its structure and the position of the hydroxyl groups will depend on the existing pH of the media.

애플리케이션

PHF may be incorporated in titanium dioxide to form a nanocomposite which can be potentially used in the photocatalysis of semiconductors. Its photothermal and therapeutic properties may be used in non-invasive image based therapy of cancer.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

Hisae Aoshima et al.
Biocontrol science, 14(2), 69-72 (2009-07-08)
The antimicrobial activities of fullerene C60 and its derivatives against 6 kinds of bacteria and 2 kinds of fungi were evaluated. The tested samples were water-soluble fullerenes (polyvinylpyrrolidone (PVP)/C60, gamma-cyclodextrin (gamma-CD)/C60, and nano-C60) and 3 types of fullerenols (C60(OH)12, C60(OH)36.8H2O
Yunxiang Sun et al.
Nanoscale, 11(24), 11933-11945 (2019-06-13)
Featuring small sizes, caged structures, low cytotoxicity and the capability to cross biological barriers, fullerene hydroxy derivatives named fullerenols have been explored as nanomedicinal candidates for amyloid inhibition. Understanding the surface chemistry effect of hydroxylation extents and the corresponding amyloid
Facile and scalable synthesis of a highly hydroxylated water-soluble fullerenol as a single nanoparticle
Kokubo K, et al.
Nano Research, 4(2), 204-215 (2011)
Synthesis and Biological Activity of Fullerenols with Various Contents of Hydroxyl Groups
Eropkin YM, et al.
Pharmaceutical Chemistry Journal, 47(2), 87-91 (2013)
Yasukazu Saitoh et al.
Journal of photochemistry and photobiology. B, Biology, 102(1), 69-76 (2010-10-15)
Polyhydroxylated fullerenes (fullerenols: C(60)(OH)(n)) are known as the major water-soluble fullerene derivatives which possess particular significance as free radical scavengers or antioxidants in biological systems. Recently, the novel polyhydroxylated fullerene (C(60) (OH)(44)·8H(2)O: SHH-F) was successfully synthesized. In the present study

문서

Single-walled carbon nanotubes (SWCNTs) are promising materials for use in the active channel of field-effect transistors (FETs), photoabsorbing layers of solar cells and photodetectors because of their ultrafast charge transport mobility.

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