777692

(1,10-Phenanthroline)(trifluoromethyl)copper(I)

90%

• 동의어(들): Trifluoromethylator^®
• 실험식(Hill 표기법): C₁₃H₈CuF₃N₂
• CAS Number: 1300746-79-5
• Molecular Weight: 312.76
• MDL number: MFCD19690901
• UNSPSC 코드: 12352101
• PubChem Substance ID: 329767921
• NACRES: NA.22

속성

• 분석: 90%
• 형태: solid
• 저장 온도: 2-8°C
• InChI: 1S/C12H8N2.CF3.Cu/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1;2-1(3)4;/h1-8H;;
• InChI key: CUQZQRIIFNWQSJ-UHFFFAOYSA-N

설명

일반 설명

(1,10-Phenanthroline)(trifluoromethyl)copper(I) [(Phen)Cu-CF₃] can be prepared by treating [CuOt-Bu]₄ with 1,10-phenanthroline, followed by the addition of (trifluoromethyl)trimethylsilane (CF₃TMS). It is an easily handled, thermally stable, single-component reagent.

애플리케이션

Trifluoromethylator, A New Arene Trifluoromethylation Reagent: (Phen)Cu-CF3

(Phen)Cu-CF₃ can be used as a reagent for the trifluoromethylation of aryl iodides. Electron-rich and electron-deficient iodoarenes, as well as sterically-hindered iodoarenes, react in high yield under mild conditions. Electrophilic functional groups, including aldehydes, nitroarenes, ketones, and esters are tolerated. The substrate scope of this reagent is broad and the reagent has wide applicability for trifluoromethylation reactions.
It can also be used in the oxidative trifluoromethylation of organoboron reagents, and terminal alkynes through C-H activation.

법적 정보

Trifluoromethylator is a registered trademark of Catylix, Inc

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302 + H312,H315,H319
• 예방조치 성명서: P264 - P280 - P301 + P312 - P302 + P352 + P312 - P305 + P351 + P338 - P332 + P313
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable