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Merck
모든 사진(2)

문서

760773

Sigma-Aldrich

Dibenzocyclooctyne-PEG4-Fluor 545

for Copper-free Click Chemistry

동의어(들):

Polyethylene glycol, ADIBO-PEG4-TAMRA, DBCO-PEG4-Fluor 545, DBCO-PEG4-TAMRA, DBCO-PEG4-tetramethylrhodamine, TAMRA DBCO

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About This Item

실험식(Hill 표기법):
C54H57N5O10
Molecular Weight:
936.06
UNSPSC 코드:
51171641
NACRES:
NA.22

형태

solid

반응 적합성

reaction type: click chemistry

저장 온도

−20°C

애플리케이션

This azadibenzocyclooctyne-tetramethyl rhodamine (TAMRA) derivative is a versatile fluorescent reagent for labeling azide containing molecules or compounds. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne click chemistry reactions.This dibenzocyclooctyne will react with azide-functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. Subsequent labeled molecules can be visualized by fluorescence spectroscopy.

Spectral Properties: Abs/Em = 545/567nm

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Rubino F. A., et al.
Journal of Visualized Experiments, 66, 4246-4246 null
Ning, X., et al.
Angewandte Chemie (International Edition in English), 47, 2253-2255 null
Single-step synthesis of small, azide-functionalized gold nanoparticles: Versatile, water-dispersible reagents for click chemistry.
Elliott EW, et al.
Langmuir (2017)
Accelerated Strain-Promoted and Oxidation-Controlled Cyclooctyne-Quinone Cycloaddition for Cell Labeling.
George A, et al.
ChemistrySelect, 2(24), 7117-7122 null
John T Ngo et al.
ACS chemical biology, 7(8), 1326-1330 (2012-06-14)
Transcriptional activity from a specified promoter can provide a useful marker for the physiological state of a cell. Here we introduce a method for selective tagging of proteins made in cells in which specified promoters are active. Tagged proteins can

문서

Copper-free click chemistry is an alternative approach to click chemistry that proceeds at a lower activation barrier and is free of cytotoxic transition metal catalysts.

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

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