720828

Indazole-6-boronic acid

• 실험식(Hill 표기법): C₇H₇BN₂O₂
• CAS Number: 885068-10-0
• Molecular Weight: 161.95
• MDL number: MFCD04972419
• UNSPSC 코드: 12352103
• PubChem Substance ID: 329763753
• NACRES: NA.22

속성

• 양식: solid
• Quality Level: 100
• mp: 112-117 °C
• 저장 온도: 2-8°C
• SMILES string: OB(O)c1ccc2cn[nH]c2c1
• InChI: 1S/C7H7BN2O2/c11-8(12)6-2-1-5-4-9-10-7(5)3-6/h1-4,11-12H,(H,9,10)
• InChI key: ZKNLCHWRWRYPGG-UHFFFAOYSA-N

설명

애플리케이션

Indazole-6-boronic acid can be used as a reactant:

• In Suzuki-Miyaura coupling reaction to synthesize indazole derivatives via C-C bond formation by reacting with different aryl halides.
• To synthesize indazole substituted purines and pyrrolo[2,3-d]pyrimidines as potential kinase inhibitors.

Reactant for preparation of:

• Bicyclic hydroxyphenylmethanone derivatives as hydroxysteroid dehydrogenase inhibitors
• Bisphosphonate inhibitors of human farnesyl pyrophosphate synthase
• Indazolyl benzoimidazoles as PKC-ζ inhibitors
• Pyrazolopyrimidinamine derivatives and their tyrosine and phosphinositide kinase inhibitory activity

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable